근치적 절제술 후 Vater씨 팽대부암의 예후 인자 및 생존율 분석
Prognostic Factors and Survival Rate of Ampulla of Vater Cancer after Curative Surgery
홍영기, 정준, 박준성, 정은주, 이용상, 박영년, 윤동섭, 최진섭, 이우정, 지훈상, 김병로,
소속 상세정보
홍영기 ( Hong Young-Ki )
연세대학교 의과대학 외과학교실
정준 ( Jeong Joon )
Anderson Cancer Center
박준성 ( Park Joon-Seong )
국군수도통합병원 외과
정은주 ( Jung Eun-Joo )
연세대학교 의과대학 외과학교실
이용상 ( Lee Yong-Sang )
연세대학교 의과대학 외과학교실
박영년 ( Park Young-Nyun )
연세대학교 의과대학 병리학교실
윤동섭 ( Yoon Dong-Sup )
연세대학교 의과대학 외과학교실
최진섭 ( Choi Jin-Sub )
연세대학교 의과대학 외과학교실
이우정 ( Lee Woo-Jung )
연세대학교 의과대학 외과학교실
지훈상 ( Chi Hoon-Sang )
연세대학교 의과대학 외과학교실
김병로 ( Kim Byong-Ro )
연세대학교 의과대학 외과학교실
KMID : 0371320040660030212
Abstract
Purpose: Ampulla of Vater cancer has a more favorable prognosis than other malignant tumors of the periampullary region, but prognostic factors have not been identified. The aim of this study was to evaluate the prognostic factors of ampulla of Vater cancer from a single hospital experience.
Methods: The medical records of the 102 patients with ampulla of Vater cancer which underwent curative surgery between 1992 and 2002, were reviewed. All specimens were critically reviewed by an expert pathologist. The relationships between survival and the clinicopathological variables were assessed.
Results: In 120 patients that presented with ampulla of Vater cancer, 102 (85%) were resected. The 5 year survival rate was 69.1%. A univariate analysis showed the survival was closely related to gender, the tumor gross morphology, invasion depth and lymph node metastasis. A multivariate analysis identified two significant factors; the depth of invasion and gender. Twenty nine of the 102 patients suffered a recurrence.
Conclusion: The depth of invasion and gender were independent significant prognostic factors of resectable ampulla of Vater cancer. Careful observation is essential for liver metastasis after surgery, especially in patients that have these factors.
키워드
팽대부 암;예후 인자;Ampullar of vater carcinoma;Prognostic factors
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