유방암 환자에서 발생한 전이성 수막암종증
Breast Cancer with Leptomeningeal Metastasis
이호균, 하일주, 김정철, 최수진나, 윤정한, 제갈영종,
소속 상세정보
이호균 ( Lee Ho-Kyun )
전남대학교 의과대학 외과학교실
하일주 ( Ha Il-Joo )
전남대학교 의과대학 외과학교실
김정철 ( Kim Jung-Chul )
전남대학교 의과대학 외과학교실
최수진나 ( Choi Soo-Jin-Na )
전남대학교 의과대학 외과학교실
윤정한 ( Yoon Jung-Han )
전남대학교 의과대학 외과학교실
제갈영종 ( Jaegal Young-Jong )
전남대학교 의과대학 외과학교실
KMID : 0371320040660030239
Abstract
Leptomeningeal metastsis (LM) is a disease where the tumor cells involves the leptomeninges. Breast cancer, of all solid tumors, is the primary tumor most frequently associated with leptomeningeal metastasis. Leptomeningeal metastasis originating from breast cancer is usually detected at an advanced stage, so its evaluation and aggressive treatment are difficult. Leptomeningeal metastasis, from solid tumors, has been reported to inexorably lead to death within 4 to 6 weeks if left untreated. ntrathecal or Intraventricular chemotherapy and radiotherarpy are the mainstays of treatment. Even though controversial, systemic chemotherapy, with regional radiotherapy, can also improve the neurological outcome and survival, without neurotoxicity. Here, two patients with leptomeningeal metastasis, originating from breast cancer, their clinical course and treatment modalities are reported.
키워드
유방암;수막암종증;Breast cancer;Leptomeningeal metastasis
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