한국 정상 성인에서의 무증상 경동맥 협착증의 유병률과 위험인자
Prevalence and Risk Factors of Asymptomatic Carotid Stenosis in Healthy Korean Population
이경복, 김동익, 조진현, 최윤호, 김선우, 문지영, 이철형, 김도율, 장영삼,
소속 상세정보
이경복 ( Lee Koung-Bok )
성균관대학교 의과대학 삼성서울병원 외과
김동익 ( Kim Dong-Ik )
성균관대학교 의과대학 삼성서울병원 혈관외과
조진현 ( Cho Jin-Hyun )
성균관대학교 의과대학 삼성서울병원 혈관외과
최윤호 ( Choi Yoon-Ho )
성균관대학교 의과대학 삼성서울병원 내과학교실
김선우 ( Kim Seon-Woo )
삼성생명과학연구소
문지영 ( Moon Ji-Young )
성균관대학교 의과대학 삼성서울병원 혈관외과
이철형 ( Lee Chul-Hyung )
성균관대학교 의과대학 삼성서울병원 혈관외과
김도율 ( Kim Do-Yool )
성균관대학교 의과대학 삼성서울병원 혈관외과
장영삼 ( Jang Young-Sam )
성균관대학교 의과대학 삼성서울병원 혈관외과
KMID : 0371320040660050415
Abstract
Purpose: To investigate the prevalence and risk factors in stenosis of the extracranial carotid artery in a healthy Korean population.
Methods: Seventeen thousand two hundred and eighty one patients, without previous history of transient ischemic attacks, amaurosis of fugax and/or any neurologic deficit, who underwent carotid artery ultrasonography, were evaluated retrospectively. The patients were divided into six groups according to the degree of carotid artery stenosis, using real time B-mode high resolution ultrasonography; Group A-normal, Group B-from 1 to 15% carotid artery stenosis, Group C-from 16 to 49% carotid artery stenosis, Group D-from 50 to 79% carotid artery stenosis, Group E-from 80 to 90% carotid artery stenosis and Group F-carotid artery occlusion (100%). Medical the records of all patients were investigated for the following factors; age, gender, diabetes mellitus, hypertension, smoking, over weight, total cholesterol, HDL-cholesterol, LDL-cholesterol, TG (triglyceride), and HbA-1c (hemoglobinA-1 c).
Results: There were 950 (5.5%) cases in Group A, 82(0.5%) in Group B, 710 (4.1%) in Group C, 138 (0.8%) in Group D, 2 (0.01%) in Group E, 18 (0.1%) in Group F. The age, total cholesterol, LDL-cholesterol, and HbA-1c were nigher in Groups B, C, D, E and F than in Group A, with statistical significance. Other factors, however, were no different among the groups.
Conclusion: Asymotomatic carotid stenosis is not uncommon in Korea. To prevent a stroke caused by carotid stenosis, carotid ultrasonography would be necessary in patients at high risk of atherosclerosis, such as hypertension, diabetes and a high serum cholesterollevel.
키워드
경동맥;동맥경화;뇌졸중;Carotid artery;Atherosclerosis;Stroke
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