유방외 파젯트병 환자에서 진단된 위암
Gastric Cancer Diagnosed in a Patient with Extramammary Paget’s Disease
이시학, 김현열, 전태용, 김동헌, 심문섭, 김문범,
소속 상세정보
이시학 ( Lee Si-Hak )
부산대학교 의과대학 외과학교실
김현열 ( Kim Hyun-Yul )
부산대학교 의과대학 외과학교실
전태용 ( Jeon Tae-Yong )
부산대학교 의과대학 외과학교실
김동헌 ( Kim Dong-Heon )
부산대학교 의과대학 외과학교실
심문섭 ( Sim Mun-Sup )
부산대학교 의과대학 외과학교실
김문범 ( Kim Moon-Bum )
부산대학교 의과대학 피부과학교실
KMID : 0371320040670040325
Abstract
Extramammary Paget’s disease (EMPD) is a rare intraepithel ial neoplasm arising in apocrine gland-bearing skin. EMPD may be regarded as a skin marker of associated malignancy because it tends to combine a variety of underlying malignancies in up to 50% of cases. Herein a case of gastric cancer diagnosed in a patient with extramammary Paget’s disease of the scrotum is reported. The patient was a 65-year-old man whose chief complaint was exanthema of the right scrotum of 3 years duration. Biopsy samples taken from patient showed large, round cells with clear cytoplasm in the epidermis. The final diagnosis was EMPD of the scrotum. The extensive workups, including tumor marker, imaging studies and endoscopy to exclude associated malignancy were performed. Examination of the endoscopic gastric biopsy spec-imen revealed an adenocarcinoma of the stomach. On the basis of this result, a radical subtotal gastrectomy was suc-cessfully performed. This case suggests that, in cases of EMPD, the clinicians should consider the possibility of underlying malignancies and thoroughly examine not only the urogenital tract and lower gastrointestinal tract, but also the visceral organs, such as the stomach, even if there are no clinical symptoms of malignancy.
키워드
유방외 파젯트병;위암;위아전절제술;Extramammary Paget`s disease;Stomach neoplasms;Subtotal gastrectomy
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