원발성 담낭암의 수술성적과 예후 인자의 분석
Surgical Outcome and Prognostic Factors of Primary Gallbladder Carcinoma
유기은, 조성호, 허진석, 최성호, 김용일, 문현종, 장원영,
소속 상세정보
유기은 ( Yu Ki-En )
성균관대학교 의과대학 삼성서울병원 외과학교실
조성호 ( Cho Sung-Ho )
성균관대학교 의과대학 삼성서울병원 외과
허진석 ( Heo Jin-Seok )
성균관대학교 의과대학 삼성서울병원 외과
최성호 ( Choi Seong-Ho )
성균관대학교 의과대학 삼성서울병원 외과학교실
김용일 ( Kim Yong-Il )
성균관대학교 의과대학 삼성서울병원 외과학교실
문현종 ( Moon Hyoun-Jong )
성균관대학교 의과대학 삼성서울병원 외과학교실
장원영 ( Chang Weon-Young )
제주대학교 의학전문대학원 외과학교실
KMID : 0371320040670050384
Abstract
Purpose: Cancer of the gallbladder, which is the eighth most common malignancy of the digestive system in Korea, is almost always associated with an unfavorable prognosis, and the clinical outcome has not improved much over the past couple of decades. This study was intended to examine our surgical experience and to evaluate the prognostic significance of the clinicopathological factors for a primary carcinoma of the gallbladder.
Methods: The data of 202 patients with gallbladder carcinomas operated on at our surgical department over a period of 10 years from May 1994 to Dec. 2003 were retrospectively reviewed.
Results: Overall, the 5-year survival was 46.8% with the median survival of 58.8 months. The histopathological type and grade, TNM stage, stage grouping, symptom, CA 19-9 level, and jaundice were significant prognostic factors. Among the 85 patients with T2 cancer, the outcome after a resection was better than that after simple cholecystectomy.
Conclusion: A complete tumor resection and no lymph node involvement are associated with a good prognosis. The long- term survival may be achieved by an early diagnosis with a curative, radical resection. Additionally, a radical resection may be beneficial for patients with a T2 gallbladder carcinoma. (J Korean Surg Soc 2004;67:384-389)
키워드
담낭암; 생존율; 예후인자; Carcinoma; Gallbladder; Survival; Prognostic factor
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