Hepatoid adenocarcinoma of the gallbladder with production of alpha-fetoprotein
이재훈, 이경근, 백승삼, 박훤겸, 이광수,
소속 상세정보
이재훈 ( Lee Jae-Hoon )
Hanyang University College of Medicine Department of Surgery
이경근 ( Lee Kyeong-Geun )
Hanyang University College of Medicine Department of Surgery
백승삼 ( Paik Seung-Sam )
Hanyang University College of Medicine Department of Pathology
박훤겸 ( Park Hwon-Kyum )
Hanyang University College of Medicine Department of Surgery
이광수 ( Lee Kwang-Soo )
Hanyang University College of Medicine Department of Surgery
KMID : 0371320110800060440
Abstract
Hepatoid adenocarcinoma (HAC) is a tumor with aberrant hepatocellular differentiation that occurs in extrahepatic organs. HAC of the gallbladder is rare, and cases of alpha-fetoprotein production are extremely rare. A 61-year-old man was diagnosed with gallbladder adenocarcinoma after laparoscopic cholecystectomy. A radical operation including resection of liver bed and lymph node dissection was performed, and no tumor cell was found. However, at postoperative 19 months, he showed lymphadenopathy of the portocaval area and tumor thrombi in the right portal vein with high levels of serum alpha-fetoprotein. After right hemihepatectomy and portahepatis lymph node dissection was performed, he was diagnosed with metastatic HAC. On reviewing the gallbladder specimen, the tumor finally demonstrated HAC as the primary origin. Despite adjuvant therapy, the patient died from multiple liver metastasis 26 months after cholecystectomy. Although HAC of the gallbladder is a very rare malignancy, awareness of its existence is critical to avoid misdiagnosis.
키워드
Hepatoid adenocarcinoma; Gallbladder; Alpha-fetoprotein
원문 및 링크아웃 정보
등재저널 정보