Short-term outcomes after laparoscopic surgery following preoperative chemoradiotherapy for rectal cancer
안병현, 이경하, 박준범, 송민상, 김지연, 김진수,
소속 상세정보
안병현 ( Ahn Byong-Hyon )
Chungnam National University Hospital Department of Surgery
이경하 ( Lee Kyung-Ha )
Chungnam National University Hospital Department of Surgery
박준범 ( Park Jun-Beom )
Chungnam National University Hospital Department of Surgery
송민상 ( Song Min-Sang )
Chungnam National University Hospital Department of Surgery
김지연 ( Kim Ji-Yeon )
Chungnam National University Hospital Department of Surgery
김진수 ( Kim Jin-Soo )
Chungnam National University Hospital Department of Surgery
KMID : 0371320120830050281
Abstract
Purpose: The safety and the feasibility of performing laparoscopic surgery for rectal cancer after preoperative chemoradiotherapy (CRT) have not yet been established. Thus, the aim of this study was to evaluate the efficacy and the safety of laparoscopic rectal cancer surgery performed after preoperative CRT.
Methods: We enrolled 124 consecutive patients who underwent laparoscopic surgery for rectal cancer. Of these patients, 56 received preoperative CRT (CRT group), whereas 68 did not (non-CRT group). The patients who were found to have distant metastasis and open conversion during surgery were excluded. The clinicopathologic parameters were evaluated and the short-term outcomes were compared between the CRT and non-CRT groups.
Results: The mean operation time was longer in the CRT group (294 minutes; range, 140 to 485 minutes; P = 0.004). In the non-CRT group, the tumor sizes were larger (mean, 4.0 cm; range, 1.2 to 8.0 cm; P < 0.001) and more lymph nodes were harvested (mean, 12.9; range, 0 to 35; P < 0.001). However, there was no significant difference between the two groups in time to first bowel movement, tolerance of a soft diet, length of hospital stay, and postoperative complication rate.
Conclusion: Performing laparoscopic surgery for rectal cancer after preoperative CRT may be safe and feasible if performed by a highly skilled laparoscopic surgeon. Randomized controlled trials and long-term follow-up studies are necessary to support our results.
키워드
Rectal neoplasm; Laparoscopy; Chemoradiotherapy; Outcomes
원문 및 링크아웃 정보
등재저널 정보