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°æÇÇÀû Æó ¼¼Ä§ÈíÀλý°ËÀÇ ±âÈä À§Çè ¿äÀÎ Risk Factors of Pneumothorax in Percutaneous Fine Needle Aspiration Biopsy of the Lung

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±è»óÁø/Sang Jin Kim ¹Ú±¤ÁÖ/½ÅÇüö/±Ç·®/Á¶º´ÁØ/¿À¼¼Á¤/¾Èâ¼ö/±èÇüÁß/Kwang Joo Park/Hyung Cheol Shin/Ryang Kwon/Byung June Jo/Sei Jung Oh/Chang Su Ahn/Hyung Jung Kim

Abstract

¸ñ Àû : °æÇÇÀû ¼¼Ä§ÈíÀλý°Ë¼úÀº ÆóÁúȯÀÇ Áø´Ü¿¡ À־ À¯¿ëÇÑ °Ë»ç·Î ³Î¸® ÀÌ¿ëµÇ°í
ÀÖÀ¸¸ç, Áø´Ü·ü°ú ¾ÈÀü¼ºÀÌ ³ôÀº °ÍÀ¸·Î ¾Ë·ÁÁ® ÀÖÀ¸³ª ±âÈä µîÀÇ ÇÕº´ÁõÀÌ ¹ß»ýÇÒ ¼ö ÀÖ´Ù.
ÀúÀÚ µîÀº ¼¼Ä§ÈíÀÎ »ý°Ë¼ú ÈÄ ¹ß»ýÇÑ ÇÕº´Áõ°ú ±âÈäÀÇ À§Çè ¿äÀο¡ °üÇÏ¿© °íÂûÇØ º¸°íÀÚ
ÇÑ´Ù.
´ë»ó ¹× ¹æ¹ý : 1990³âºÎÅÍ 1996³â±îÁö ¿©·¯ °¡Áö Æóº´º¯À¸·Î ¼¼Ä§ÈíÀÎ »ý°Ë¼úÀ» ½ÃÇàÇÑ
157¿¹ÀÇ Àǹ«±â·Ï°ú ¹æ»ç¼±¼Ò°ßÀ» ÈÄÇâÀûÀ¸·Î °ËÅäÇÏ¿© »ý°Ë¼ú ÈÄ ÇÕº´Áõ ¹ß»ýÀÇ ¾ç»ó, Ä¡
·á ¹× °æ°ú, ±âÈäÀÇ À§Çè ¿äÀÎ µîÀ» Á¶»çÇÏ¿´°í, ±âÈäÀÇ ¹ß»ýÀ» ¿¹ÃøÇÒ ¼ö ÀÖ´Â À§Çè ¿äÀÎÀ¸
·Î´Â º´º¯ÀÇ Å©±â, º´º¯±îÁöÀÇ °Å¸®, »ý°ËħÀÇ ±½±â, »ý°Ë Ƚ¼ö, »ç¿ëÇÑ ¿µ»ó±â±â, Æó±â´É °Ë
»ç µî¿¡ ´ëÇØ ºÐ¼®ÇÏ¿´´Ù.
°á °ú : ÇÕº´ÁõÀº 157¿¹Áß 40¿¹(25.5%)¿¡¼­ ¹ß»ýÇÏ¿´°í, ÀÌ Áß ±âÈäÀÌ 26¿¹(16.7%), °´Ç÷ÀÌ
11¿¹(7%), Ç÷ÈäÀÌ 2¿¹(1.3%)¿´À¸¸ç, »ý°ËºÎÀ§ÀÇ È亮¿¡ ¾ÏÀÇ ÀüÀÌ°¡ 1¿¹ ÀÖ¾ú´Ù. º´º¯¿¡¼­
È丷±îÁöÀÇ °Å¸®°¡ ¸Ö¼ö·Ï ±âÈäÀÌ ¸¹ÀÌ ¹ß»ýÇÏ¿´´Ù(2cm¹Ì¸¸±º, 12.9% ; 2-4cmÀαº, 24.4%
; 4cm ÀÌ»ó±º, 57.1%[p<0.05]). Æó±â´É °Ë»ç»ó ³ë·Â¼º ÆóÈ°·®(FVC, forced vital capacity)Àº
µÎ ±º¿¡¼­ °¢°¢ 2.6¡¾0.9L ¹× 3.1¡¾0.8L·Î ±âÈäÀÌ ¹ß»ýÇÑ ±º¿¡¼­ À¯ÀÇÇÏ°Ô ³·¾ÒÀ¸³ª(p<0.05),
1ÃÊ°£ ³ë·Â¼º È£±â·®(FEV1, forced expiratory volume in 1 second), FEV1ÀÇ ¿¹ÃøÄ¡¿¡ ´ë
ÇÑ ºñÀ²(FEV1%), FEV1/FVCºñ, FVCÀÇ ¿¹ÃøÄ¡¿¡ ´ëÇÑ ºñÀ²(FVC%) µîÀº À¯ÀÇÇÑ Â÷ÀÌ°¡
¾ø¾ú´Ù. º´¼Ò°¡ È丷¿¡ ºÙ¾î ÀÖ¾ú´ø °æ¿ì¿¡ ±âÈäÀÇ ¹ß»ý·üÀÌ 9%·Î È丷¿¡ ºÙ¾î ÀÖÁö ¾ÊÀº
°æ¿ìÀÇ 26%¿¡ ºñÇØ À¯ÀÇÇÏ°Ô ³·¾Ò´Ù(P<0.01). ±× ¿Ü º´º¯ÀÇ Å©±â, »ý°Ë Ƚ¼ö, »ý°ËħÀÇ ±½
±â, »ç¿ëÇÑ ¿µ»ó±â±â µîÀº ±âÈäÀÇ ¹ß»ý°ú ¿¬°ü¼ºÀÌ ¾ø´Â °ÍÀ¸·Î ³ªÅ¸³µ´Ù.
°á ·Ð : Æó ¼¼Ä§ÈíÀλý°Ë½Ã ±âÈäÀÇ ¹ß»ý¿¡´Â º´º¯±îÁöÀÇ °Å¸® ¹× °ø±â°¡ Â÷ ÀÖ´Â ÆóÀÇ Åë
°ú ¿©ºÎ°¡ À¯ÀÇÇÑ À§Çè¿äÀÎÀÌ´Ù.
#ÃÊ·Ï#
Purpose : Percutaneous fine needle aspiration biopsy is known to be a useful diagnostic
method for the diagnosis of various pulmonary diseases. Its diagnostic yield is high, and
it is safe, but complications such as pneumothorax can occasionally occur. We reviewed
the complications arising after needle aspiration biopsy and analyzed the risk factors of
pneumothorax.
Materials and Methods : The medical records and radiographic studies of 157 patients
with various pulmmonary diseases who underwent needle aspiration biopsy of the lung
between 1990 and 1996 were retrospectively reviewed. The climical features, treatment,
and courses of complications were reviewed, and risk factors of pneumothorax such as
depth and size of lesion, diameter of needle, number of punctures, and obstructive
pulmonary abnormalities were analyzed.
Results : Complications occurred in 40 of 157 cases(25.5%), namely pneumothorax in
26(16.6%), hemoptysis in 11(7%), hemothorax in two(1.3%), and recurrence of
malignancy at the site of aspiration in one(0.6%). When the patients were divided into
three groups according to depth of lesion, there were sugnificant difference in the
incidence of pneumothorax ; the results were as follows : less than 2cm, 12.9% ;
between 2 and 4cm, 24.1% ; and larger than 57.1%(p<0.05). In pulmonary function
testing, FVC(forced vital capacity) of patients with pneumothorax was less than that of
patients without(2.6¡¾0.9L vs 3.1¡¾0.8L, p<0.05), but FEV1(forced espiratory volume in 1
second), FEV1%(percentage of predicted FEV1), FEV1/FVC, and FVC%(percentage of
predicted FEV) were not different between the two group. The incidence of
pneumothorax in patients with pleura-attached lesion(9%) was lower than that of those
with non-attached lesion(26%, p=0.01). The age of patients, size of lesion, diameter of
the neeedle, guidance methods and number of aspirations showed no significant
relationship with pneumothorax.
Conclusion : In needle aspiration biopsy of the lung, depth of lesion and passage of a
needle through aerated lung are significant risk factors of pneumothorax.

Å°¿öµå

Biopsies; Complications; Lung; biopsy; Pneumothorax;

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