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Abstract

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#ÃÊ·Ï#
Purpose : To evaluate the MRI findings helpful in differentiating between osteoporosis
and metastatic vertebral compression fracture.
Materials and Methods : This study involved 52 patients with nontraumatic vertebral
compression fracture ; 23 had osteoporosis and 29, metastatic diseases, We
retrospectively analyzed signal abnormality and the extent to which bone marrow was
seen within the involved vertebral body, sharpness of margin of abnormal signal
intensity, morphological characteristics of the vertebral endplate, and the presence or
absence of posterior element unvolvement and paraspinal mass, as seen on T1- and
T2-weighted MR images.
For statistical analysis, the chi-square test was used.
Results : In 14 of 23 patients (61%) with osteoporotic benign compression, and 27 of 29
(93%) with metastatic compression fracture, the bone marrow of the compressed
vertebral body showed both low signal intensity on T1-weighted image and high signal
intensity on T2-weighted image.
In 13 of 14 osteoporotic compression fractures, the extent of abnormal bone marrow
signal was incomplete, but in 20 of 27 metastic compression fractures, this was
complete. In all 13 cases of osteoporosis, incomplete abnormal signal showed a sharp
margin, whereas in five of seven metastatic compression fractures, this margin was
ill-defined. Morphologically, the endplate was concave in 20 of 23 osteoporosis
cases(87%), but was angled in 13 of 29 metastatic compression fractures (45%). Only
the latter showed verebral posterior element involvement (21/29) and paraspinal mass
(16/29).
Conclusion : The extent of signal abnormality, margin of compressed bone marrow,
morphologic characteristics of the endplate, and the presence or absence of posterior
element involvment and paraspinal mass on T1- and T2-weighted MR images, as
described above, may be helpful in differentiating between benign osteoporotic and
malignant metastatic compression fractures.

Å°¿öµå

Spine; fractures; Spine; MR; Spine; mineralization; Spine; secondary neoplasms;

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