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Abstract

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¾Æ 218¸íÀ» ´ë»óÀ¸·Î ÇÏ¿´´Ù. ¹Ì¼÷¾Æ±ºÀº ´Ù¾çÇÑ ÁÖ»ê±â ¹®Á¦·Î ½Å»ý¾Æ ÁýÁß Ä¡·á½Ç¿¡¼­ Ä¡
·á¸¦ ¹ÞÀº ȯ¾ÆµéÀ̾ú´Ù. »ó¿Ï°ñ ±ÙÀ§ºÎ °ñ´Ü °ñÈ­ Áß½ÉÀÇ Æò°¡´Â ´Ü¼ø ÈäºÎ »çÁø¿¡¼­ Æò°¡
ÇÏ¿´´Ù. ¹Ì¼÷¾Æ±ºÀÇ °æ¿ì ±³Á¤ ³ªÀ̸¦ Á¤ÇÏ¿´´Âµ¥, ±³Á¤ ³ªÀÌ´Â ¼öÅ ³ªÀÌ°¡ 40ÁÖ°¡ µÇ´Â ½Ã
Á¡À» 0°³¿ù·Î ÇÏ¿´´Ù. ¹Ì¼÷¾Æ±º¿¡¼­ ¾òÀº ´Ü¼ø ÈäºÎ »çÁøÀº 0°³¿ùÀÏ ¶§ 42°³, 1°³¿ù¿¡ 40°³,
2°³¿ù¿¡ 37°³, 3°³¿ù¿¡ 36°³¿´´Ù. ¸¸»è¾Æ±ºÀº 0°³¿ù¿¡ 103°³, 1°³¿ù¿¡ 42°³, 2°³¿ù¿¡ 42°³, 3
°³¿ù¿¡ 31°³ÀÇ ´Ü¼ø ÈäºÎ »çÁøÀ» ¾ò¾ú´Ù. ¹Ì¼÷¾Æ±ºÀº Ç÷û alkaline phosphatase, Ä®½·, ÀÎÄ¡
¸¦ ÃøÁ¤ÇÏ°í ¼Õ¸ñ¿¡ ´ëÇÑ ´Ü¼ø ÃÔ¿µÀ» ÇÏ¿´´Ù.
ÀÌ·¸°Ô Çؼ­ ¹Ì¼÷¾Æ±º°ú ¸¸»è¾Æ±º °£¿¡ »ó¿Ï°ñ ±ÙÀ§ºÎ °ñ´Ü °ñÈ­ Áß½ÉÀÇ ÃâÇö ºóµµ°¡ °¢
±³Á¤ ³ªÀ̺°·Î Â÷ÀÌ°¡ ÀÖ´ÂÁö º¸¾Ò°í, ¹Ì¼÷¾Æ±º³»¿¡¼­´Â ¿øÀÎ Áúȯ¿¡ µû¸¥ °ñÈ­ Áß½ÉÀÇ Ãâ
Çö ºóµµ¿¡ Â÷ÀÌ°¡ ÀÖ´ÂÁö, Ç÷ûÇÐÀû ÁöÇ¥ÀÇ ÀÌ»óÀ¯¹«¿Í ¼Õ¸ñÀÇ ´Ü¼øÃÔ¿µ»ó ÀÌ»ó À¯¹«¿¡ µû
¶ó °ñÈ­ Áß½ÉÀÇ ÃâÇö ºóµµ¿¡ Â÷ÀÌ°¡ ÀÖ´ÂÁö ¾Ë¾Æº¸¾Ò´Ù. À̵鰣ÀÇ Åë°èÇÐÀû ºñ±³¿¡´Â
Fisher's Exact Test¸¦ »ç¿ëÇÏ¿´´Ù.
°á °ú : ¹Ì¼÷¾Æ±ºÀº ±³Á¤ ³ªÀÌ 0°³¿ùÀÏ ¶§ 2.4%(1/42), 1°³¿ù¿¡´Â 20.0%(8/40), 2°³¿ù¿¡´Â
43.2%(16/37), 3°³¿ù¿¡´Â 69.4%(25/36)¿¡¼­ »ó¿Ï°ñ ±ÙÀ§ºÎ °ñ´Ü¿¡ °ñÈ­ Áß½ÉÀÌ º¸¿´°í, ¸¸»è
¾Æ±ºÀº 0°³¿ù¿¡ 24.3%(25/103), 1°³¿ù¿¡ 66.7%(28/42), 2°³¿ù¿¡ 83.3%(35/42), 3°³¿ù¿¡
90.3%(28/31)¿¡¼­ »ó¿Ï°ñ ±ÙÀ§ºÎ °ñ´Ü¿¡ °ñÈ­ Áß½ÉÀÌ º¸¿´´Ù. 0°³¿ù, 1°³¿ù, 2°³¿ùÀÏ ¶§ ¹Ì
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Â÷ÀÌ°¡ ¾ø¾ú´Ù(p>0.05). ¶ÇÇÑ ¹Ì¼÷¾Æ±º³»¿¡¼­´Â ¿øÀÎ Áúȯ¿¡ µû¸¥ °ñÈ­ Áß½ÉÀÇ ÃâÇö ºóµµÀÇ
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Â÷ÀÌ´Â ¾ø¾ú´Ù(p>0.05).
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ÀÇ °ñÈ­ Á᫐ ÃâÇö ºóµµ°¡ Àû´Ù.
#ÃÊ·Ï#
Purpose : To assess the difference in the appearance of the proximal humeral
epiphyseal ossification center, as seen on chest radiograph, between preterm and
full-term infants at the same corrected ages.
Materials and Methods : Forty two preform infants born at 26-35 weeks of gestational
age and 218 normal full-term infants born at 38-42 weeks were investigated. Because of
various perinatal problems, the preterm infants were treated at a neonatal intensive care
unit. Proximal humeral epiphyseal ossification centers were evaluated from chest
radiographs, and in cases of preterm infants, the corrected age of 0 month was defined
as postconceptional 40 weeks. In preterm infants, the numbers of chest radiographs
obtained were 42 at 0 month, 40 at 1 month, 37 at 2 month and 36 at 3 month of
corrected age, while in those who were full-term, the numbers were 103 cases at 0
month, 42 at 1 month, 42 at 2 months and 31 at 3 months of age. In the preterm group,
alkaline phosphatase, calcium, phosphorus levels and simple wrist radiographs were
checked.
We then evaluated the difference of appearance of the proximal humeral epiphyseal
ossification center between preterm and full-term infants at the same corrected ages, as
well as the difference between causative diseases, between the normal and abnormal
serologic group and between the normal and abnormal wrist group in preterm infants at
the same corrected ages, Using Fisher's exact test, the data were analysed
Results : The incidences of the proximal humeral epiphyseal ossification center in
preform infants were 2.4% (1/42) at 0 month, 20.0% (8/40) at 1 month, 43.2% (16/37) at
2 months and 69.4% (25/36) at 3 months ; in full-term infants, the figures were
24.3%(25/103) at 0 month, 66.7%(28/42) at 1 month, 83.3%(35/42) at 2 months and
90.3%(28/31) at 3 months. At 0, 1, and 2 months, the incidences were thus seen to be
lower in preterm than infull-term infants(p<0.001), though at w months there was no
difference(p>0.05). In preterm infants, there were no statistical differences between
causative the normal and abnormal serlogic group and between the normal and abnormal
wrist group(p>0.05).
Conclusion : Up to the age of two months, the proximal humeral epiphyseal ossification
center of preterm infants appears later than that of full-term infants at the same
corrected age.

Bones; growth and development; Bones; epiphysis; Infants; newborn; skeletal system; Fetus; skeletal system.;

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