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ȲÀç¿õ/Jae Woong Hwang ±èÀ¯°æ/ȲÁ¤È­/±èżº/³ë´ö¿ì/ÀÌ°æ¼ö/Yookyung Kim/Jung Hwa Hwang/Tae Sung Kim/Duk Woo Ro/Kyung Soo Lee

Abstract

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Purpose : To present initial and follow-up HRCT findings of lymphangitic
carcinomatosis of the lung.
Materials and Methods : Both initial and follow-up HRCT scans were obtained in 18
patients with lymphangitic carcinomatosis of the lung. After dividing the patients into
two groups (with anticancer chemotherapy (n=12) and without chemotherapy (n=6)),
changes of pulmonary parenchymal abnormalities (percentile increase or decrease in the
extent of each pattern) were assessed and compared on initial and follow-up HRCTs.
Results : Findings on initial CT were interlobular septal thickening (n=18) (smooth in
15 and mixed smooth and nodular in three), thickening of bronchovascular bundles (n=
17), areas of ground-class opacity (n=15), polygonal lines (n=15), and nodules (n=10).
With chemotherapy, the finding of polygonal lines decreased by 20.3%, while findings of
ground-glass opacity, bronchovascular bundle thickening, septal thickening, and nodules
remained stable. Without chemotherapy, all CT patterns of abnormalities except nodules
increased by 45-88%. In three patients who did not undergo chemotherapy, smooth
interlobular septal thickening chanced to nodular thickening.
Conclusion Lymphangitic carcinomatosis of the lung manifests initially as smooth
thickening of the interlobular septae, bronchovascular bundle thickening, areas of
ground-class opacity, and polygonal lines, as seen on HRCT Without chemotherapy, the
extent of CT findings increases and there is a tendency for smooth septal thickening to
change to nodular thickening. Chemotherapy induces improvement or cessation of the
progression of CT findings.

Å°¿öµå

Lung neoplasms; metastases Lymphatic system; neoplasms Lung neoplasms; CT;

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