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Æó¾Ï¿¡ ÀÇÇÑ È丷 ÆÄÁ¾ÀÇ Àü»êÈ­´ÜÃþÃÔ¿µ ¼Ò°ß CT Finding of Pleural Dissemination from Lung Cancer

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ÃÖµÎȯ/Du Hwan Choe ¼ÕÁ¤Àº/ÀÌÅÂÇö/±è±âȯ/Áø¼öÀÏ/Á¶ÀçÀÏ/Jeong Eun Sohn/Tae Hyun Lee/Kie Hwan Kim/Soo Yil

Abstract

¸ñÀû: Æó¾ÏÀÇ È丷 ÆÄÁ¾(Pleural dissemination)ÀÇ CT¼Ò°ß°ú ±× Áø´ÜÀû °¡Ä¡¿¡ ´ëÇÏ¿© ¾Ë¾Æ
º¸°íÀÚ ÇÏ¿´´Ù.
´ë»ó ¹× ¹æ¹ý: ¿ø¹ß¼º Æó¾ÏÀ¸·Î °³Èä¼úÀ» ½ÃÇàÇÑ È¯ÀÚµéÀÇ Àü»êÈ­µÈ ÀÚ·á·ÎºÎÅÍ, °³Èä¼ú ½Ã
¿¡ È丷ÆÄÁ¾ÀÌ È®ÀÎµÈ 23¸íÀ» ´ë»óÀ¸·Î ÇÏ¿´°í, °°Àº ÀÚ·á·ÎºÎÅÍ È丷 ÆÄÁ¾ÀÌ ¾ø¾ú´ø 50¸í
ÀÇ ´ëÁ¶±ºÀ» ¹«ÀÛÀ§·Î ÃßÃâÇÏ¿´´Ù. À̵é ȯÀÚÀÇ Àǹ« ±â·Ï°ú ¼ö¼úÀü CT¼Ò°ßÀ» ÈÄÇâÀûÀ¸·Î
ºÐ¼®ÇÏ¿´À¸¸ç, °¢ ¼Ò°ßÀÇ ºóµµ¸¦ ´ë»ó±º°ú ´ëÁ¶±º »çÀÌ¿¡¼­ ºñ±³ÇÏ¿´´Ù.
°á°ú: È丷 ÆÄÁ¾ÀÌ ÀÖ¾ú´ø 23¸íÀÇ CT»ó¿¡¼­ ¼¼°¡Áö ÇüÅÂÀÇ È丷 ºñÈÄ(ÇöóÅ©Çü, °áÀýÇü, ¿±
°£¿­ÀÇ ºñÈÄ) Áß¿¡¼­ ÇÑ°¡Áö ÀÌ»óÀ» º¸¿´´ø °æ¿ì°¡ 17¿¹·Î, °¡Àå ÀǹÌÀÖ´Â ÆǺ°·ÂÀ» º¸¿´´Ù
(¹Î°¨µµ, 74%: ƯÀ̵µ, 60%: p=0.007). ±× ¹Û¿¡ CT»ó Á¾¾çÀÌ È丷°ú ÀÎÁ¢ÇÏ°í ÀÖ´Â ¼Ò°ß, Á¾
¾çÀÇ Á¶Á÷ÇÐÀû À¯ÇüÀÌ ¼±¾ÏÀÎ °æ¿ì, ¹× ¼ö¼úÀü ±â°üÁö°æ °Ë»ç»ó¿¡¼­ ±â°üÁö³»ÀÇ º´º¯ÀÌ ¾ø
¾ú´ø °æ¿ì µîÀÌ ÆǺ°·Â ÀÖ´Â ¼Ò°ßÀ¸·Î ³ªÅ¸³µ´Ù(p<0.05). È丷 ºñÈÄÀÇ ¼Ò°ß°ú ÇÔ²² ÀÌµé ¼Ò
°ßÀÇ Á¶ÇÕÀ» ÀÌ¿ëÇÏ¿© È丷 ÆÄÁ¾À» Áø´ÜÇϸé ƯÀ̵µ¸¦ Çâ»ó½Ãų¼ö ÀÖ¾ú´Ù.
°á·Ð: Æó¾ÏÀÇ ¼ö¼úÀü CT»ó¿¡¼­ ¹Ì¼¼ÇÑ È丷 ºñÈÄÀÏÁö¶óµµ À̸¦ ÀνÄÇϸé È丷 ÆÄÁ¾ÀÇ Áø´Ü
¿¡ µµ¿òÀ» ÁÙ °ÍÀ¸·Î ±â´ëµÈ´Ù. ƯÈ÷, Á¾¾çÀÌ CT»ó¿¡¼­ È丷°ú ÀÎÁ¢ÇÏ¿© Àְųª, Á¶Á÷ÇÐÀû
À¸·Î ¼±¾ÏÀ̰ųª, ±â°üÁö³»ÀÇ º´º¯À» º¸ÀÌÁö ¾Ê´Â °æ¿ì¿¡ È丷 ÆÄÁ¾ÀÇ °¡´É¼ºÀº ´õ¿í ³ô¾Æ
Áø´Ù°í »ý°¢µÈ´Ù.
#ÃÊ·Ï#
Purpose : The purpose of our study was to identify the CT findings that help detect
pleural dissemination from lung cancer and to evaluate the usefulness of selected
diagnostic criteria.
Materials and Methods : After a computerized database search of 606 patients who had
undergone thoracotomy for primary lung cancer, 23 patients were identified as having
surgically documented pleural dissemination. From the same database, 50 patients
without pleural dissemination during thoracotomy were randomly selected as controls.
Preoperative CT scans and medical records were reviewed retrospectively, and findings
were compared between the two groups.
Results : One of more of three types of pleural thickening (plaque-like, nodular, and
fissural) were identified on CT as the most discriminating finding(sensitivity, 74%:
specificity, 60%; p=0.007). The following findings were also significantly discriminating
(p<0.05):contiguity of primary tumor with the pleural surface as seen on CT
adenocarcinoma in cell type; and a peripheral tumor defined as one in which
bronchoscopy revealed no endobronchial lesion. The use of combinations of these
findings in addition to pleural thickening rendered diagnostic criteria more specific at the
cost of the sensitivity.
Conclusion : During preoperative CT evaluation of lung cancer, the recognition of subtle
pleural thickening helps detect pleural dissemination. The likelihood that subtle pleural
thickening represents pleural dissemination is increased when a primary tumor is
contiguous with the pleural surface, is an adenocarcinoma, or is peripherally located.

Å°¿öµå

Lung neoplasms CT; Lung neoplasms metastases; Lung neoplasms staging; Pleura CT; Pleura neoplasms;

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