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Abstract

¸ñÀû:µ¿¸Æ±â ¿µ»ó¿¡¼­ ÀϹÝÀûÀÎ °£¼¼Æ÷¾ÏÀÇ Æ¯Â¡Àû ¼Ò°ßÀ» º¸ÀÌÁö ¾Ê´Â °£¼¼Æ÷¾ÏÀÇ ¼ö¼úÀü ¿µ
»óÁø´Ü½ÃÀÇ ÁÖÀÇÁ¡°ú ¼ö¼úÈÄ º´¸® Á¶Á÷ÇÐÀû ¼Ò°ß°ú ºñ±³ÇÏ°íÀÚ ÇÏ¿´´Ù.
´ë»ó°ú ¹æ¹ý:ÀÌÁ߽ñâ CT»ó µ¿¸Æ±â ¡¤Áö¿¬±â ¸ðµÎ¿¡¼­ ±ÕÀÏÇÑ ÀúÀ½¿µÀ¸·Î °üÂûµÇ°í,º´¸®ÀûÀ¸
·Î´Â Á¾±« ³»ºÎÀÇ 95%ÀÌ»óÀÌ ÀÀ°í±«»ç·Î ÀÌ·ç¾îÁø °£¼¼Æ÷¾Ï 4¿¹¸¦ ´ë»óÀ¸·Î ÇÏ¿´´Ù.ÀÌÁß½Ã
±â CT ¼Ò°ß,ÃÊÀ½ÆÄ¿Í Ç÷°üÁ¶¿µ ¾ç»ó,Lipiodol CT(LiCT)ÀÇ ¾ç»óÀ» º´¸® Á¶Á÷ÇÐÀû ¼Ò°ß°ú ºñ
³»ºÎ¿¡ ±¤¹üÀ§ÇÑ ÀÀ°í±«»ç¸¦ µ¿¹ÝÇÑ °£¼¼Æ÷¾Ï:
±³ÇÏ¿´´Ù.
°á°ú:ÀÌÁ߽ñâ CT ¼Ò°ß»ó °áÀýÀÇ Å©±â´Â 30-50 mm·Î Æò±Õ 41 mm¿´°í,¸ð¾çÀº ±¸Çü(3¿¹)
ȤÀº ³­¿øÇü(1¿¹)À̾úÀ¸¸ç,µ¿¸Æ±â ¡¤Áö¿¬±â ¸ðµÎ¿¡¼­ ±ÕÀÏÇÑ ÀúÀ½¿µÀÇ Á¾±«·Î °üÂûµÇ¾ú´Ù.ÃÊ
À½ÆÄ °Ë»ç»ó ¸ðµç ¿¹¿¡¼­ ³»ºÎ¿¡ÄÚ¸¦ °üÂûÇÒ ¼ö ÀÖ¾ú°í ÇǸ·À» ³ªÅ¸³»´Â Àú¿¡ÄÚÀÇ ´Þ¹«¸®(halo)
°¡ °üÂûµÇ¾ú´Ù.Ç÷°üÁ¶¿µ ¶Ç´Â LiCT»ó º¯¿¬ ÀϺΠȤÀº Á᫐ ÀϺο¡¼­ Á¾¾çÀÇ ¹Ì¼¼ÇÑ ¿°»ö ¶Ç
´Â ¹Ì¹ÌÇÑ ¸®ÇÇ¿Àµ¹ ÁýÀûÀ» º¼ ¼ö ÀÖ¾ú´Ù.º´¸®¼Ò°ß»ó ÀýÁ¦ÇÑ 3¿¹ ¸ðµÎ ¿ÏÀüÇÑ ÇǸ·À» °¡Áö°í
ÀÖ¾ú°í,Á¶Á÷±¸Á¶´Â ¸ðµÎ »ö»óÇü(trabecular type)À§ÁÖ¿´À¸¸ç,ºÐÈ­µµ´Â Edmondson µî±Þ II,
IIIÀ̾ú°í,Á¾±«ÀÇ 95%ÀÌ»óÀÌ ÀÀ°í±«»çµÇ¾î ÀÖ¾ú´Ù.
°á·Ð:ÀÌÁ߽ñâ CT»ó µ¿¸Æ±â ¡¤Áö¿¬±â ¸ðµÎ¿¡¼­ ÀúÀ½¿µÀ¸·Î °üÂûµÇ´õ¶óµµ °æÈ­¼º°£À» °¡Áø B
Çü °£¿° Ç׿ø ¾ç¼º ȯÀÚ¿¡¼­´Â ÀÀ°í±«»ç¸¦ ÁÖ·Î ÇÏ´Â °£¼¼Æ÷¾ÏÀÇ °¡´É¼ºÀ» °í·ÁÇØ¾ß Çϸç,ÃÊ
À½ÆÄ»ó ³»ºÎ ¿¡ÄÚ°¡ ÀÖ°í ÇǸ·ÀÇ Á¸ÀçÇÏ ´Â °æ¿ì¿¡´Â °£¼¼Æ÷¾Ï¿¡ ÁØÇÑ Ãß°¡ÀûÀÎ °Ë»ç¸¦ ¹Ýµå
½Ã ½ÃÇàÇÏ¿©¾ß ÇÑ´Ù.

Purpose: The aim of this study is to correlate the non-characteristic dual-phase CT imaging findings of hepato-cellular carcinoma with the observed characteristics of surgical specimens.
Materials and Methods: We studied four cases in which homogeneous low attenuation was observed during the arterial and delayed phases of dynamic CT scanning and in which hepatocellular carcinoma with coagulation necrosis above 95% was
pathologically
confirmed. We compared the findings of dual phase CT scanning, ultrasonography, angiography and Lipiodol CT scanning with the observed features of surgical specimens.
Results: Nodules were 30 -50 (mean, 41) mm in size, and were round in three cases and oval in one. In all four cases, a low density lesion was observed during the arterial and delayed phases of dual-phase CT scanning. Ultrasonography demonstrated
internal echo and the presence of a hypoechoic halo, implying that in all cases a capsule was present. At angiography and LiCT, minimal peripheral and central tumor staining or lipiodol up-take was observed. In all surgical specimens a complete
capsule
was visible, and histologic structures were mainly of the trabecular type, Edmondson grade II or III was recorded, and the mass had undergone extensive coagulation necrosis (above 95%).
Conclusion: In cirrhotic liver which is hepatitis B-antigen positive, clear sonographic findings of internal echo and a capsule, rather than a simple cyst, indicate the possibility of hepatocellular carcinoma with extensive co-agulation necrosis.
This
is so even if the arterial and delayed phases of dual-phase CT scanning indicate the presence of a low-density lesion, and in such cases additional work-up is therefore required.

Å°¿öµå

Liver neoplasms; Liver; cirrhosis; Liver; necrosis;

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µîÀçÀú³Î Á¤º¸

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