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Abstract

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Purpose: To evaluate the usefulness of diffusion-weighted imaging after intracranial surgery in patients with
intracranial tumors.
Materials and Methods: Within ten days of intracranial surgery, diffusion-weighted MR images were obtained
in 68 patients with intracranial tumors which included meningioma (n=31), glioma (n=21), neurogenic tumor
(n=4), hemangiopericytoma (n=3), and in three cases involved metastasis. The signal intensity of the resected
margin and adjacent parenchyma was visually assessed on diffusion-weighted images, and the signal intensi-ties
on seen T1-and T2-weighted images were also analyzed. In patients with newly developed hyperintense
lesions in parenchyma adjacent to the resection sites seen on postoperative T2-weighted images, apparent dif-fusion
coefficients (ADC) were calculated and analyzed on follow-up MR images.
Results: Immediate postoperative diffusion-weighted images showed various signal intensities at the resected
margins visible on conventional and diffusion-weighted MR images. In 15 patients, newly developed hyperin-tense
lesions adjacent to resected sites were seen on postoperative T2-weighted images. On diffusion-weighted
images, nine of these lesions were hyperinteuse and and were shown by follow-up MR imaging to be subject
to focal tissue loss and atrophy, and six were isointense but with no sign of tissue loss or atrophy. Among the
15 patients with postoperative lesions near the site of tumorectomy, diffusion-weighted imaging showed that
the ADC values of hyperintense lesions were significantly lower than those of isointense lesions (independent
sample t-test: p<0.05).
Conclusion: In patients with intracranial tumors, immediate postoperative diffusion-weighted imaging is use-ful
for differentiating between ischemic tissue damage and vasogenic edema.

Å°¿öµå

Brain; MR; Brain; diffusion; Brain; neoplasms;

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