Àá½Ã¸¸ ±â´Ù·Á ÁÖ¼¼¿ä. ·ÎµùÁßÀÔ´Ï´Ù.

Àڱà °æºÎ¾ÏÀÌ ÀÖ´Â °¡Àӱ⠿©¼º¿¡¼­ ¹æ»ç¼±Ä¡·á ÀüÈÄ ÀÚ±â°ø¸í¿µ»ó¿¡¼­ ³­¼ÒÀÇ º¯È­ Change of Ovary Before and After Radiotherapy in Reproductive Women with Cervix Carcinoma in MR Imaging

´ëÇѹæ»ç¼±ÀÇÇÐȸÁö 2001³â 45±Ç 6È£ p.621 ~ 625
¼Ò¼Ó »ó¼¼Á¤º¸
Á¶¿µ¹Î/Young Min Cho Á¤¿ë¿¬/°­Çü±Ù/ÀÓÈ¿¼ø/À±¿õ/Á¤Å¿õ/¼­Á¤Áø/Yong Yeon Jeong/Heoung Keun Kang/Hyo Soon Lim/Woong Yoon/Tae Woong Chung/Jeong Jin Seo

Abstract

¸ñÀû:Àڱà °æºÎ¾ÏÀ» °¡Áø °¡Àӱ⠿©¼º¿¡¼­ ¹æ»ç¼± Ä¡·á ÀüÈÄ ³­¼ÒÀÇ º¯È­¸¦ Àڱ⠰ø¸í(Magnetic
Resonance,MR)¿µ»ó¿¡¼­ ¾Ë¾Æº¸°íÀÚ ÇÏ¿´´Ù.
´ë»ó°ú ¹æ¹ý:ÀڱðæºÎ¾ÏÀÌ ÀÖ´Â °¡Àӱ⠿©¼º¿¡¼­ ¹æ»ç¼±Ä¡·á¸¦ ÇÏ°í Ä¡·á Àü°ú ÈÄ¿¡ MR °Ë»ç
¸¦ ½ÃÇàÇÑ 33¸íÀ» ´ë»óÀ¸·Î ÇÏ¿´´Ù.ÃÑ ¹æ»ç¼± Á¶»ç·®Àº Æò±Õ 11,279cGy (ü¿Ü Æò±Õ:5,352
cGy,ü³» Æò±Õ:5,927 cGy)¿´´Ù.MR ÃßÀû ¿µ»óÀº Ä¡·á µµÁß(n=29)ȤÀº Ä¡·á ÈÄ(n=4)¿¡ ¾ò
¾ú´Ù.MR ¿µ»óÀº ȯÀÚÀÇ È¾´Ü¸é T1 °­Á¶¿µ»ó,Ⱦ´Ü¸é°ú ½Ã»ó¸é T2°­Á¶¿µ»óÀ» ¾ò¾ú´Ù.µÎ ¸í
ÀÇ ¹æ»ç¼±°ú ÀÇ»çÀÇ ÇÕÀÇ ÇÏ¿¡ ³­¼ÒÀÇ Á¸Àç À¯¹«,³­¼ÒÀÇ Å©±â,³­¼Ò´ç ³¶Á¾ÀÇ ¼ö¿Í ³­¼ÒÀÇ ¼ö
Áú°ú ÇÇÁúÀÇ ±¸¿ª ±¸ºÐ À¯¹«¸¦ ºÐ¼®ÇÏ¿´´Ù.
°á°ú:¸ðµç ȯÀÚ´Â ¿ù°æÀÇ ¼Ò½ÇÀÌ ÀÖ¾ú´Ù.¹æ»ç¼±Ä¡·á Àü MR ¿µ»ó¿¡¼­´Â 94%(62/66),Ä¡·á ÈÄ
MR ¿µ»ó¿¡¼­´Â 39%(26/66)¿¡¼­ ³­¼Ò°¡ ¹ß°ßµÇ¾ú´Ù(p <.05).³­¼ÒÀÇ Æò±Õ Å©±â´Â ¹æ»ç¼±Ä¡
·á Àü 2.6 ¡¿1.9 ¡¿2.2 cm,Ä¡·á ÈÄ¿¡´Â 1.7 ¡¿1.3 ¡¿1.4 cm ¿´´Ù(p <.05).³­¼Ò ´ç ³¶Á¾ÀÇ ¼ö´Â
¹æ»ç¼±Ä¡·á Àü Æò±Õ 5.1°³,Ä¡·á ÈÄ Æò±Õ 3.1°³¿´´Ù(p <.05).T2°­Á¶¿µ»ó¿¡¼­ ³­¼ÒÀÇ ±¸¿ª ±¸
ºÐÀº ¹æ»ç¼±Ä¡·á Àü 74%(46/62),Ä¡·á ÈÄ¿¡´Â 15%(4/26)¿¡¼­ °¡´ÉÇÏ¿´´Ù(p <.05).
°á·Ð:Àڱà °æºÎ¾Ï ȯÀÚ¿¡¼­ ¹æ»ç¼± Ä¡·á ÈÄ ³­¼Ò ¹ß°ßÀ² ¹× Å©±â°¡ °¨¼ÒÇÏ¿´°í,³­¼ÒÀÇ ±¸¿ª
±¸ºÐÀÌ ºÒ°¡´ÉÇØÁø °æ¿ì°¡ ¸¹¾Ò´Ù.ÀÌ´Â Á¤»óÀûÀÎ Æó°æ±â ³­¼ÒÀÇ º¯È­¿Í À¯»çÇϸç MR ¿µ»óÀÌ
¹æ»ç¼± Ä¡·áÈÄ ³­¼ÒÀÇ ±¸Á¶Àû º¯È­¸¦ ¹Ý¿µÇÒ ¼ö ÀÖ´Ù°í »ý°¢µÈ´Ù.

Purpose: To investigate changes in the ovary revealed by MR imaging before and after radiotherapy in pre-menopausal
patients with cervical carcinoma.
Materials and Methods: Thirty-three premenopausal patients with cervical carcinoma underwent radiation
therapy at an average dosage of 11,279 (external: 5,352; internal: 5,927) cGy. Before and after this therapy, all
underwent pelvic MR imaging using a 1.5T MR scanner (GE Medical Systems, Milwaukee, U.S.A.). The aver-age
interval of follow-up MR imaging was 7.2 months, and axial T1-weighted and axial and sagittal T2-weight-ed
MR images were obtained. The presence, size number of follicles, and differentiation of the zonal anatomy
of the ovary were determined by two radiologists, who reached a consensus.
Results: After radiation therapy, all patients ceased menstruation. For ovaries, the detection rates before and
after radiation therapy were 94% (62/66) and 39% (26/66) (p<0.05), respectively, and average ovary size was
2.6 ¡¿1.9 ¡¿2.2 cm before and 1.7 ¡¿1.3 ¡¿1.4 cm after therapy (p<0.05). The average number of ovarian follicles
before and after therapy was 5.1 and 3.1, respectively (p<0.05). T2-weighted imaging, demonstrated differen-tiation
of zonal anatomy in 74% of cases (46/62) before radiotheraphy, and 15% (4/26) after (p<0.05).
Conclusion: Our study has shown that after radiation therapy in premenopausal patients with cervical cancer,
detection rates, average size, and the number of ovaries decreased, findings which are similar to those for nor-mal
postmenopausal ovary. MR imaging can reveal structural change in ovaries.

Ovary; Ovary; MR; Radiations; injurious effects; Radiations; injurious effects; complications of therapeutic radiology;

Å°¿öµå

¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸

µîÀçÀú³Î Á¤º¸

KoreaMed
KAMS