핵산증폭검사 판정불능 결과를 보인 헌혈 혈액에서 HCV 또는 HIV 표지자 연관성 조사
Investigation of the Association of HCV or HIV Markers in Non-Discriminated Blood Donations
강정원, 신선미, 강재원, 서영익, 민혁기, 김명한,
소속 상세정보
강정원 ( Kang Jung-Won )
대한적십자사 혈액수혈연구원
신선미 ( Shin Sun-Mi )
대한적십자사 중앙혈액검사센터
강재원 ( Kang Jae-Won )
대한적십자사 혈액수혈연구원
서영익 ( Seo Young-Ik )
대한적십자사 혈액수혈연구원
민혁기 ( Min Hyuk-Ki )
대한적십자사 혈액수혈연구원
김명한 ( Kim Myung-han )
대한적십자사 혈액관리본부
Abstract
HBV core antibody and surface antibody test are currently conducted for those donors showing non-discriminated reactive (NDR) results on a nucleic acid amplification test (NAT) as a blood donor screening assay. It is necessary to investigate the relationship with HCV or HIV in the donors showing NDR results. From June 12th, 2012 to December 31st, 2018, 0.05% (9,020/17,798,461) donors showed NDR results on a NAT. Among the donors showing NDR results, 17 and 18 donors showed positive results on serological assay of HCV and HIV, respectively. 23 donors with NDR results showed positive results on the serological assay or NAT for HCV or HIV on the following donation. Further study and more accumulated data are required because it may be difficult to find the cause of NDR results by the current serological assay that is used for screening blood donors.
키워드
Non-discriminated reactive; Nucleic acid amplification test; HCV; HIV
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