ABO 부적합 고형장기 이식에서의 수혈
Transfusion in ABO-Incompatible Solid Organ Transplantation
김형석, 고대현,
소속 상세정보
김형석 ( Kim Hyung-Suk )
Seoul National University Hospital Department of Laboratory Medicine
고대현 ( Ko Dae-Hyun )
University of Ulsan College of Medicine Asan Medical Center Department of Laboratory Medicine
Abstract
ABO-incompatible solid organ transplantation (ABOi TPL) is a widely accepted treatment option for treating end-stage renal or liver diseases. Although the appropriate selection of the ABO blood group for transfusion is a key step for successful ABOi TPL, there are no evidence-based guidelines to cope with this issue. In this letter, we suggest appropriate blood selection criteria for ABOi TPL based on the basic principles of ABO incompatibility. For major mismatched ABOi TPL, red blood cells (RBCs) should be of the organ recipient’s ABO group, while platelets (PLTs) and plasma products should be of the donor’s ABO group. For the bidirectional mismatched cases, it is desirable to select recipient type RBCs and group AB PLTs and plasma products.
키워드
ABO-incompatible transplantation; Blood group incompatibility; Blood transfusion
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