과량의 Ibuprofen 복용 후 저나트륨혈증과 전신부종을 보인 신생아 1례
Hyponatremia and Generalized Edema Associated with Ibuprofen Therapy in a Neonate
김소희, 김은영, 박상기,
소속 상세정보
김소희 ( Kim So-Hee )
조선대학교 의과대학 소아과학교실
김은영 ( Kim Eun-Young )
조선대학교 의과대학 소아과학교실
박상기 ( Park Sang-Kee )
조선대학교 의과대학 소아과학교실
KMID : 0438520060130010176
Abstract
Ibuprofen is a nonsteroidal anti-inflammatory, analgesic, and antipyretic agent which has used for the treatment of rheumatoid and musculoskeletal disorders. Its side effects have generally been minor; these include dyspepsia, anorexia, nausea and vomiting, constipation, rashes, dizziness, and tinnitus. Ibuprofen is a prostaglandin synthetase inhibitor that is not recommended for neonates. It is pharmacologically similar to indomethacin, which is used to treat symptomatic patent ductus arteriosus in premature infants. We report here a case of a term infant who developed severe hyponatremia and generalized edema associated with the ingestion of an overdose of ibuprofen. The baby made a complete recovery. (J Korean Soc Neonatol 2006;13:176-179)
키워드
Ibuprofen;Hyponatremia;Generalized edema;Neonate
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