Àá½Ã¸¸ ±â´Ù·Á ÁÖ¼¼¿ä. ·ÎµùÁßÀÔ´Ï´Ù.

°Ç°­ °ËÁøÀÚ¿¡¼­ ¿ª·ù¼º ½Äµµ¿°ÀÇ À¯º´·ü ¹× À§Çè ÀÎÀÚ¿¡ ´ëÇÑ È¯ÀÚ-´ëÁ¶±º ¿¬±¸ The Prevalence and Risk Factors of Reflux Esophagitis in Routine Check-up Subjects

´ëÇѼÒÈ­±âÇÐȸÁö 1998³â 32±Ç 6È£ p.701 ~ 708
¼Ò¼Ó »ó¼¼Á¤º¸
Àü¼º±¹ ÀÌdz·Ä/½Å¸íÈñ/ÇöÀç±Ù/ÀÌÈ­¿µ/¼ÕÁ¤ÀÏ/±èÀçÁØ/°í±¤Ã¶/¹é½Â¿î

Abstract

¿ä¾à
¸ñÀû : ¿ª·ù¼º ½Äµµ¿°Àº ¼­¾ç¿¡¼­´Â 10-20%·Î ºñ±³Àû ºóµµ°¡ ³ôÀº °ÍÀ¸·Î ¾Ë·ÁÁ® ÀÖÀ¸³ª,
¿ì¸®³ª¶ó¸¦ Æ÷ÇÔÇÑ µ¿¾ç¿¡¼­´Â º¸°í ÀÚü°¡ ¸¹Áö ¾Ê°í, ºóµµµµ 10% À̳»·Î ³·Àº °ÍÀ¸·Î ¾Ë
·ÁÁ® ÀÖ´Ù. ¶ÇÇÑ ¿ª·ù¼º ½Äµµ¿°À» ÀÏÀ¸Å°´Â µ¥ °ü¿©ÇÏ´Â ÀÎÀÚ´Â ¿©·¯ °¡Áö°¡ °Å·ÐµÇ°í ÀÖÀ¸
³ª, ü°èÀûÀÎ ¿¬±¸´Â ¸¹Áö ¾ÊÀº ½ÇÁ¤ÀÌ´Ù. ÀÌ¿¡ ÀúÀÚ µîÀº ÀϹÝÀΰú À¯»çÇÑ Áý´ÜÀ̶ó°í ÇÒ
¼ö ÀÖ´Â °Ç°­ °ËÁøÀÚ¿¡¼­ ¿ª·ù¼º ½Äµµ¿°ÀÇ À¯º´·ü°ú À§Çè ÀÎÀÚ¸¦ ¾Ë¾Æº¸°íÀÚ ÇÏ¿´´Ù.
´ë»ó ¹× ¹æ¹ý : 1³â°£ À§ ³»½Ã°æÀ» Æ÷ÇÔÇÑ °Ç°­ °ËÁøÀ» ¹ÞÀº 8,314¸íÀ» ´ë»óÀ¸·Î ÇÏ¿´°í,
³²ÀÚ°¡ 4,876¸í(18-83¼¼), ¿©ÀÚ°¡ 3,438¸í(20-77¼¼)À̾ú´Ù. ¸ðµç ¼öÁøÀÚ´Â Èí¿¬·Â, À½ÁÖ·Â, ½Ä
À̽À°ü, ¿îµ¿·Â, ¾à¹° º¹¿ë·Â ¹× Áúȯ·Â¿¡ ´ëÇÑ ¼³¹®Áö¸¦ ÀÛ¼ºÇÏ¿´´Ù. À§ ³»½Ã°æ°Ë»ç °á°ú¿¡
ÀÇÇÑ ¿ª·ù¼º ½Äµµ¿°ÀÇ À¯º´·üÀ» ±¸ÇÏ¿´´Ù. ¿ª·ù¼º ½Äµµ¿°ÀÌ ÀÖ¾ú´ø ¼öÁøÀÚ¸¦ ȯÀÚ±ºÀ¸·Î ÇÏ
°í, ¿ª·ù¼º ½Äµµ¿°ÀÌ ¾ø¾ú´ø ¼öÁøÀÚ Áß¿¡¼­ ȯÀÚ±º°ú ¿¬·É, ¼ºº° ¹× °ÅÁÖÁö¸¦ ¸ÂÃß¾î 2¹è¼ö
¸¦ ¹«ÀÛÀ§·Î ¼±Á¤ÇÏ¿© ´ëÁ¶±ºÀ¸·Î ÇÑ È¯ÀÚ-´ëÁ¶±º ¿¬±¸¸¦ ÅëÇØ À§ÇèÀÎÀÚ¸¦ ºÐ¼®ÇÏ¿´´Ù.
°á°ú : ¿ª·ù¼º ½Äµµ¿°ÀÇ ±â°£ À¯º´·üÀº ³²ÀÚ°¡ 3.73%, ¿©ÀÚ°¡ 0.81%¿´À¸¸ç, ³²ÀÚ¿¡¼­ À¯ÀÇ
ÇÏ°Ô ³ô¾Ò´Ù(p<0.01). 1990³â ¿ì¸® ³ª¶ó 18¼¼ ÀÌ»ó Àα¸ ±¸Á¶·ÎºÎÅÍ ÃßÁ¤µÈ ¿¬·ÉÇ¥ÁØÈ­ À¯
º´·üÀº ³²ÀÚ°¡ 3.19%, ¿©ÀÚ°¡ 1.66%¿´´Ù. ȯÀÚ±º(200¸í)°ú ´ëÁ¶±º(400¸í)À» ´ë»óÀ¸·Î À§Çè
ÀÎÀÚ ºÐ¼® °á°ú, ´Üº¯·® ºÐ¼®¿¡¼­´Â 23 PY ÀÌ»óÀÇ Èí¿¬·Â ¹× BMI°¡ Åë°èÀûÀ¸·Î À¯ÀÇÇÏ°Ô
¿ª·ù¼º ½Äµµ¿°°ú °ü°èµÇ¾ú°í(p<0.05), À̵éÀ» µ¿½Ã¿¡ º¸Á¤ÇÑ ´Ùº¯·® ºÐ¼®¿¡¼­´Â 23 PY ÀÌ»ó
ÀÇ Èí¿¬·Â¸¸ÀÌ Åë°èÀûÀ¸·Î À¯ÀÇÇÑ À§ÇèÀÎÀÚ¿´´Ù(p<0.05).
°á·Ð : °Ç°­ °ËÁøÀÚ¿¡¼­ ¿ª·ù¼º ½Äµµ¿°ÀÇ À¯º´·üÀº ³²ÀÚ°¡ 3.73%, ¿©ÀÚ°¡ 0.81%¿´°í, ³²ÀÚ
¿¡¼­ À¯ÀÇÇÏ°Ô À¯º´·üÀÌ ³ô¾Ò´Ù. ±×¸®°í Èí¿¬·ÂÀÌ ¿ª·ù¼º ½Äµµ¿°ÀÇ À¯ÀÇÇÑ À§Çè ÀÎÀÚ¿´´Ù.
#ÃÊ·Ï#
Background/Aims : There were few epidemiological data on reflux esophagitis in
Korea. The aim of this study was to estimate the prevalence and risk factors of reflux
esophagitis in Korea.
Methods : We examined 8314 subjects (male 4,876, female 3,438, age: 18-83 year)
visiting health promotion center for routine check-up including EGD. All of them were
given a questionnaire about smoking, alcohol consumption, exercise, diet habits, use of
drugs and medical history. We estimated the prevalence of reflux esophagitis and
performed a case-control study to evaluate the risk factors of reflux esophagitis. We
recruited 200 cases with reflux esophagitis and 400 controls without reflux esophagitis
on EGD.
Results : The prevalence of reflux esophagitis was 3.73% in male and 0.81% in female.
The age-adjusted prevalence was 3.19% in male and 1.66% in female. The prevalence in
male was significantly higher than that in female (p<0.01). On the monovariate analysis,
smoking and body mass index were significantly related with reflux esophagitis
(p<0.05). On the multivariate analysis, smoking was a significant risk factor of reflux
esophagitis (p<0.05).
Conclusions : The prevalence of reflux esophagitis in subjects who had routine
check-up was 3.73% in male and 0.81% in female. Smoking is suggested to be a
significant risk factor of reflux esophagitis.

Å°¿öµå

¿ª·ù¼º ½Äµµ¿°; ¿ªÇÐ; À§½Äµµ ¿ª·ùÁúȯ; Reflux esophagitis; Epidemiology; Gastroesophageal reflux disease;

¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸

 

µîÀçÀú³Î Á¤º¸

MEDLINE
KCI
KoreaMed
KAMS