골수로의 원격전이를 동반한 위장의 저등위 점막연관성 림프조직림프종 2예
Two Cases of Gastric Low-grade Mucosa-associated Lymphoid Tissue Lymphoma Involving Bone Marrow
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1이미헌/1Mi Hun Lee
1정훈용/1장혜숙/1명승재/1양석균/1홍원선/1김진호/1민영일/2강경훈/1Hwoon-Yong Jung/1Hye Sook Chang/1Seung Jae Myung/1Suk-Kyun Yang/1Weon-Seon Hong/1Jin Ho Kim/1Young I1 Min/2Gyeong Hoon Kang
KMID : 0614620000360050695
Abstract
-Abstract-
Extranodal mucosa-associated lymphoid tissue (MALT) lymphoma constitutes most of
the low-grade gastric lymphoma and almost 50％ of all gastric lymphoma. The specific
recirculation pattern might explain the tendencies of MALT lymphomas to remain
localized and to recur preferentially within the gastrointestinal tract. It was known that
the rate of gastric MALT lymphoma with bone marrow involvement was low, as less
than 10％. We have experienced two patients who presented with nonspecific abdominal
pain and dyspepsia. They were diagnosed to have gastric low-grade MALT lymphoma
with bone marrow involvement at the time of presentation. The endoscopic findings
showed irregular ulcerations. Microscopically, there was monotonous lymphoid infiltration
with lymphoepithelial lesions which were consistent with low grade MALT lymphoma.
Both patients showed H. pylori-associated chronic gastritis. The results of their bone
marrow biopsy showed focal infiltration of neoplastic lymphoid cells. We report two
cases of primary gastric low-grade MALT lymphoma with the bone marrow
involvement.
키워드
저등위 점막연과성 림프조직림프종; 골수 침범; 헬리코박터 파이로리의 제균; Gastric MALT lymphoma; Bone marrow involvement;
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