조기위암의 근치적 치료로서 내시경적 점막절제술의 유용성
Usefulness of Endoscopic Mucosal Resection for Curative Treatment of Early Gastric Cancer
현동효, 정석, 이진우, 정봉주, 류성태, 이창근, 김명식, 권계숙, 이돈행, 김범수, 김형길, 신용운, 김영수,
소속 상세정보
현동효 ( Hyun Dong-Hyo )
인하대학교 의과대학 내과학교실
정석 ( Jeong Seok )
인하대학교 의과대학 내과학교실
이진우 ( Lee Jin-Woo )
인하대학교 의과대학 내과학교실
정봉주 ( Jeong Bong-Joo )
인하대학교 의과대학 내과학교실
류성태 ( Ryu Sung-Tae )
인하대학교 의과대학 내과학교실
이창근 ( Lee Chang-Kun )
인하대학교 의과대학 내과학교실
김명식 ( Kim Myung-Sik )
인하대학교 의과대학 내과학교실
권계숙 ( Kwon Kye-Sook )
인하대학교 의과대학 내과학교실
이돈행 ( Lee Don-Haeng )
인하대학교 의과대학 내과학교실
김범수 ( Kim Pum-Soo )
인하대학교 의과대학 내과학교실
김형길 ( Kim Hyung-Gil )
인하대학교 의과대학 내과학교실
신용운 ( Shin Yong-Woon )
인하대학교 의과대학 내과학교실
김영수 ( Kim Young-Soo )
인하대학교 의과대학 내과학교실
KMID : 0614620030420060453
Abstract
BACKGROUND/AIMS: Endoscopic mucosal resection (EMR) has been widely accepted as a curative treatment of early gastric cancer (EGC). The aim of this study was to determine the usefulness and limitations of EMR for treatment of EGC by analyzing our own experience.
METHODS: We retrospectively evaluated 51 EGC lesions (45 mucosal and 6 submucosal cancers) from 49 patients who had undergone EMR between Oct. 1997 and Aug. 2002 at Inha Universtiy Hospital.
RESULTS: Among 45 lesions of mucosal cancer, enbloc resection was performed in 13 lesions and piecemeal resection in 32 lesions. Complete resection rates of enbloc and piecemeal resection were 84.6% and 43.8%, respectively (p=0.012). Complete resection rate of the lesions smaller than 1 cm in size was 71.4%, 1 to 2 cm in size 52%, and greazter than 2 cm in size 37.5%. Complete resection rates of well, moderately, and poorly differentiated EGC were 59.4%, 71.4%, and 16.7%, respectively (p=0.048). Thirty-three patients underwent a follow-up endoscopy at I month after EMR and two were found to have residual cancers. One patient who had a piecemeal EMR showed cerical and abdominal lymph node metastasis 10 months after EMR.
CONCLUSIONS: In selected patients with EGC, EMR can be a curative treatment modality. However, complete resection rate is low in large sized and poorly differentiated EGCs and when piecemeal resection is performed.
키워드
조기위암;내시경적 점막절제술
Stomach neoplasms;Early gastric cancer;Endoscopic mucosal resection
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