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¿©½ÂÀç ( Yeo Seong-Jae ) 
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Á¶Ã¢¹Î ( Cho Chang-Min ) 
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Á¤¹Î±Ô ( Jung Min-Kyu ) 
°æºÏ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
¼­¾È³ª ( Seo An-Na ) 
°æºÏ´ëÇб³ ÀÇ°ú´ëÇÐ º´¸®Çб³½Ç
¹èÇÑÀÍ ( Bae Han-Ik ) 
°æºÏ´ëÇб³ ÀÇ°ú´ëÇÐ º´¸®Çб³½Ç

Abstract


Background/Aims: Determining the cause of suspected biliary stricture is often challenging in clinical practice. We aimed to compare the diagnostic yields of endoscopic ultrasound-guided tissue sampling (EUS-TS) and endoscopic retrograde cholangiopancreatography-guided tissue sampling (ERCP-TS) in patients with suspected biliary stricture at different primary lesions.

Methods: We enrolled patients who underwent same-session EUS- and ERCP-TS for the evaluation of suspected biliary stricture. Forceps biopsy and/or brush cytology of intraductal lesions and fine-needle aspiration for solid mass lesions were performed during ERCP and EUS, respectively.

Results: One hundred and twenty-five patients treated at our institution between January 2011 and September 2016, were initially considered for the study. However, 32 patients were excluded due to loss of follow-up (n=8) and ERCP-TS on the pancreatic duct (n=20) or periampullary lesions (n=4). Of the 93 patients included, 86 had a malignant tumor including cholangiocarcinoma (n=39), pancreatic cancer (n=37), and other malignancies (n=10). Seven patients had benign lesions. EUS-TS had higher rate of overall diagnostic accuracy than ERCP-TS (82.8% vs. 60.2%, p=0.001), and this was especially true for patients with a pancreatic lesion (84.4% vs. 51.1%, p=0.003).

Conclusions: EUS-TS was found to be superior to ERCP-TS for evaluating suspected biliary strictures, especially those caused by pancreatic lesions.

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Endosonography; Cholangiopancreatography, endoscopic retrograde; Diagnosis; Stricture

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