궤양성 대장염 환자에서 메살라진 좌약으로 인하여 재발한 호산구성 폐렴
Recurrent Eosinophilic Pneumonia Associated with Mesalazine Suppository in a Patient with Ulcerative Colitis
박명린, 이정의, 강상범, 박연희,
소속 상세정보
박명린 ( Park Myoung-Rin )
보훈공단 대전보훈병원 내과
이정의 ( Lee Jung-Uee )
가톨릭대학교 의과대학 대전성모병원 병리과
강상범 ( Kang Sang-Bum )
가톨릭대학교 의과대학 대전성모병원 내과
박연희 ( Park Yeon-Hee )
가톨릭대학교 의과대학 대전성모병원 내과
Abstract
Mesalazine suppositories are widely used to treat ulcerative colitis and have a guaranteed safety profile, but although rare, they can cause pulmonary toxicity. A 35-year-old woman with ulcerative colitis was diagnosed to have acute eosinophilic pneumonia after 29 days of oral mesalazine use and improved after mesalazine and corticosteroid were withdrawn. Reintroduction of mesalazine suppositories resulted in acute eosinophilic pneumonia recurrence after 28 days. Mesalazine re-administration (even via a different route) in patients with a history of mesalazine-induced eosinophilic pneumonia should be undertaken cautiously, because eosinophilic pneumonia may recurrence.
키워드
Mesalazine; Mesalamine; Suppositories; Eosinophilic pneumonia; Pulmonary eosinophilia
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