비셀리악 글루텐 과민성
Non-celiac Gluten Sensitivity
차라리, 김현진,
소속 상세정보
차라리 ( Cha Ra-Ri )
경상대학교 의과대학 창원경상대학교병원 소화기내과
김현진 ( Kim Hyun-Jin )
경상대학교 의과대학 창원경상대학교병원 소화기내과
Abstract
Non-celiac gluten sensitivity (NCGS) is a term that is used to describe individuals who are not affected by celiac disease or wheat allergy, yet they have intestinal and/or extra-intestinal symptoms related to gluten ingestion with improvement of their symptoms upon withdrawing gluten from their diet. Gluten-related disorder groups are manifested by symptoms of gastrointestinal tract disorders, as well as hematological dermatological endocrinological, gynecological, rheumatological and nervous system symptoms. It is believed that NCGS represents heterogeneous groups with different subgroups characterized by different etiologies, clinical histories and clinical courses. There also appears to be an overlap between NCGS and irritable bowel syndrome (IBS). There is a need for establishing strict criteria for diagnosing NCGS. The absence of validated biomarkers remains a significant limitation for research studies on NCGS. New evidence shows that a gluten-free diet may be beneficial for some patients with gastrointestinal symptoms, such as those symptoms commonly found in patients with IBS. Further studies about NCGS are needed.
키워드
Nonceliac gluten sensitivity; Functional gastrointestinal disorders; Abdominal pain; Diarrhea; Glutens
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