국내 성인 캠필로박터 장염의 임상 양상: 단일 기관 후향적 연구
Clinical Characteristics of Campylobacter Enterocolitis in Korean Adults: A Retrospective Study at a Single Center
유민석, 정숙희, 박영숙, 오일환, 채원영, 김수형, 이기영, 송치우, 손병관, 김성환, 조영관, 정광현, 이효영, 채정돈,
소속 상세정보
유민석 ( Yoo Min-Seok )
Eulji University School of Medicine Nowon Eulji Medical Center Department of Internal Medicine
정숙희 ( Chung Sook-Hee )
Anyang Sam Hospital Department of Internal Medicine
박영숙 ( Park Young-Sook )
Eulji University School of Medicine Nowon Eulji Medical Center Department of Internal Medicine
오일환 ( Oh Il-Hwan )
Eulji University School of Medicine Nowon Eulji Medical Center Department of Internal Medicine
채원영 ( Chae Won-Young )
Eulji University School of Medicine Nowon Eulji Medical Center Department of Internal Medicine
김수형 ( Kim Soo-Hyung )
Eulji University School of Medicine Nowon Eulji Medical Center Department of Internal Medicine
이기영 ( Lee Ki-Young )
Eulji University School of Medicine Nowon Eulji Medical Center Department of Internal Medicine
송치우 ( Song Chi-Woo )
Eulji University School of Medicine Nowon Eulji Medical Center Department of Internal Medicine
손병관 ( Son Byoung-Kwan )
Eulji University School of Medicine Nowon Eulji Medical Center Department of Internal Medicine
김성환 ( Kim Seong-Hwan )
Eulji University School of Medicine Nowon Eulji Medical Center Department of Internal Medicine
조영관 ( Jo Young-Kwan )
Eulji University School of Medicine Nowon Eulji Medical Center Department of Internal Medicine
정광현 ( Jung Kwang-Hyun )
Eulji University School of Medicine Nowon Eulji Medical Center Department of Internal Medicine
이효영 ( Lee Hyo-Young )
Eulji University School of Medicine Nowon Eulji Medical Center Department of Internal Medicine
채정돈 ( Chae Jeong-Don )
Eulji University School of Medicine Nowon Eulji University Hopsital Department of Laboratory Medicine
Abstract
Background/Aims: Although the diarrheal disease caused by Campylobacter bacteria has been continuously increasing in Korea, there has been limited study on the clinical aspects of Campylobacter enteritis in adults in Korea. The purpose of this study was to analyze the clinical features and characteristics of adult patients with Campylobacter enteritis.
Methods: This retrospective study included patients diagnosed with Campylobacter enterocolitis at Nowon Eulji University Hopsital between January 2016 and December 2017. Campylobacter enterocolitis was diagnosed through polymerase chain reaction of stools from patients with acute diarrhea.
Results: Among 630 hospitalized patients with acute diarrhea, Campylobacter enterocolitis was diagnosed in 88 patients (14.0%). The mean age was 37.9±19.1 years. Campylobacter enterocolitis was most prevalent in the summer (52 patients, 59.1%). Patients exhibited more than 10 times of diarrhea in 36 (40.9%), high fever above 39°C in 19 (21.59%), and abdominal pain above 5 points on the numeric rating scale in 23 (26.14%) cases. In abdominal CT scan, pancolitis was found in 58 patients (65.9%). Small intestine was involved in 37 patients (42.4%). Mean CRP was 10.14 mg/dL (range 0.72-32.27 mg/dL). The duration of diarrhea after antibiotics treatment was 2.34±1.51 days in the ciprofloxacin treatment group and 2.26±1.71 days in the 3rd cephalosporin treatment group.
Conclusions: Campylobacter enterocolitis was common during summer. Commonly healthy young adults were hospitalized due to severe symptoms of Campylobacter enterocolitis. Whole colon and small bowel were frequently involved. Most patients were treated with antibiotics, and the efficacy of 3rd cephalosporin treatment was not inferior to that of ciprofloxacin treatment.
키워드
Campylobacter; Enterocolitis; Adult
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