Oxaliplatin-induced Sudden Hearing Loss in a Patient with Pancreatic Cancer
김승범, 김소영, 김국현, 김태년,
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김승범 ( Kim Sung-Bum )
Yeungnam University College of Medicine Department of Internal Medicine
김소영 ( Kim So-Yeong )
Yeungnam University College of Medicine Department of Internal Medicine
김국현 ( Kim Kook-Hyun )
Yeungnam University College of Medicine Department of Internal Medicine
김태년 ( Kim Tae-Nyeun )
Yeungnam University College of Medicine Department of Internal Medicine
Abstract
Oxaliplatin is a new generation of platinum derivatives used frequently to treat solid organ malignancies, including colorectal and ovarian cancer. Recently, an oxaliplatin-based chemotherapeutic regimen was adopted for advanced pancreatic cancer. Although oxaliplatin has extensive therapeutic potential, its use can be limited by significant adverse effects, particularly ototoxicity. This paper reports a rare case of irreversible unilateral hearing loss in a 48-year-old female that developed after the intravenous infusion of oxaliplatin during pancreatic cancer treatment. To the best of the authors’ knowledge, this is the second reported case of oxaliplatin-related ototoxicity in pancreatic cancer.
키워드
Ototoxicity; Oxaliplatin; Chemotherapy; Pancreatic neoplasms
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