토끼의 혈청콜레스테롤 함량에 미치는 리놀레산과 리포단백질의 상호작용
The effect of inferaction between cinoleic acid and Lipoprotein on serum cholesterol level in the rabbit
광주보건전문대학논문집 1981년 6권 1호 p.37 ~ 46
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남현근
KMID : 0615219810060010037
Abstract
The effect of interaction between linoleic acid and lipoprotein on rabbit blood serum cholesterol level was studied for a period of 4 weeks using isocalories and isonitrogenous diets. Linoleic acid added to the basal diet and vegetable oils. The subject rabbits were divided into 4 feeding groups such as A(basal diet only), B(basal+sesame oil＋casein＋linoleic acid), C(basal＋soybeanoil＋casein＋linoleic acid) and D(basal＋perilla oil＋casein＋linoleic acid).
The results are summarized as follows:
1. Serum cholesterol(㎎/1㎖. serum) of the A,B,C and D group was 79.55, 112.65, 116.55 and 98.0 respectively. Cholesterol ester was 45.2% for A group, 65.5% for B group, 70.5% for C group and 53.7% for D group.
2. Serum triglyceride(mg/100ml.serum) of the A,B,C and Dwas 121.5, 128.7, 138.7 and 130.7 repsectively.
3. Serum lipalbumin(㎎/100㎖. serum) of the A,B,C and D group was 3.31, 3.45, 3.33 and 3.44 respectively. Beta-lipoprotein was 0.71 for A group, 0.68 for B group, 0.80 for C group and 0.57 for D group.
4. The percentage of lipalbumin and beta-lipoprotein were 57.3, 12 for A group; 64.1, 11.5 for B group; 47.0, 13.7 for C group and 49.0, 9.6 for D group. The ratio of beta-lipoprotein per lipalbumin was 2.4 for A group, 1.97 for B group, -2.14 for C group and 1.65 for D group.
5. The mobility of lipalbumin and beta-lipoprotein of the A,B,C and D group were 3.8, 9.4, 4.4, 11.6; 4.4, 12.6, 5.0, 12.8 respectively. The ratio of linoleic acid per ilpalbumin was 2.5 for B group, 2.1 for C group and 1.9 for D group.
6. Addition of linoleic acid causes an increase in the mobility of beta-lipoprotein, and this effect is considered to be due to association of linoleic anions with the lipoprotein. This electrokinetic anion causes more mobility increase to the anodic direction.
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