HIV-1 p24 단백질에 대한 단클론항체의 isotyping과 cross-reaction
Isotyping and Cross-reaction of mouse anti-HIV-1 p24 Monoclonal Antibodies
광주보건전문대학논문집 1995년 20권 1호 p.155 ~ 162
소속 상세정보
이영종/Lee YJ
KMID : 0615219950200010155
Abstract
In order to improve the relizbility immunodiagnostic techniques being used in the diagnostic of HIV-1, mouse anti-HIV-1 p24 monoclonal antibodies were isotyped and cross-reacted.
When monoclonal antibodies against HIV-1 p24 protein were isotyped, they were confirmed IgG_2b/? which H and L chain were y_2b and k chain, respectively.
To confirm the cross-reaction for another viral proteins, mouse anti-HIV-1 p24 IgG_2b/? was reacted with HBV proteins. However, the reaction did not occur. Thus, it was confirmed that mouse anti-HIV-1 p24 IgG_2b/? only bound to HIV-1 p24 protein.
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원문 및 링크아웃 정보
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