Second Asian Consensus on Irritable Bowel Syndrome
Gwee Kok Ann, Gonlachanvit Sutep, Ghoshal Uday C., Chua Andrew S. B., Miwa Hiroto, Wu Justin, 박영태, 이오영, Lu Ching-Liang, 박효진, Chen Minhu,
소속 상세정보
( Gwee Kok Ann )
National University of Singapore Yong Loo Lin School of Medicine Department of Medicine
( Gonlachanvit Sutep )
Chulalongkorn University Faculty of Medicine Department of Medicine
( Ghoshal Uday C. )
Sanjay Gandhi Postgraduate Institute of Medical Sciences Department of Gastroenterology
( Chua Andrew S. B. )
Gastro Centre Ipoh
( Miwa Hiroto )
Hyogo College of Medicine Department of Internal Medicine
( Wu Justin )
Chinese University of Hong Kong Faculty of Medicine Department of Medicine and Therapeutics
박영태 ( Bak Young-Tae )
Korea University College of Medicine Department of Internal Medicine
이오영 ( Lee Oh-Young )
Hanyang University College of Medicine Department of Internal Medicine
( Lu Ching-Liang )
Taipei Veterans General Hospital Endoscopy Center for Diagnosis and Treatment
박효진 ( Park Hyo-Jin )
Yonsei University College of Medicine Gangnam Severance Hospital Department of Internal Medicine
( Chen Minhu )
Sun Yat-Sen University First Affiliated Hospital Department of Gastroenterology
Abstract
Background/Aims: There has been major progress in our understanding of the irritable bowel syndrome (IBS), and novel treatment classes have emerged. The Rome IV guidelines were published in 2016 and together with the growing body of Asian data on IBS, we felt it is timely to update the Asian IBS Consensus.
Methods: Key opinion leaders from Asian countries were organized into 4 teams to review 4 themes: symptoms and epidemiology, pathophysiology, diagnosis and investigations, and lifestyle modifications and treatments. The consensus development process was carried out by using a modified Delphi method.
Results: Thirty-seven statements were developed. Asian data substantiate the current global viewpoint that IBS is a disorder of gut-brain interaction. Socio-cultural and environmental factors in Asia appear to influence the greater overlap between IBS and upper gastrointestinal symptoms. New classes of treatments comprising low fermentable oligo-, di-, monosacharides, and polyols diet, probiotics, non-absorbable antibiotics, and secretagogues have good evidence base for their efficacy.
Conclusions: Our consensus is that all patients with functional gastrointestinal disorders should be evaluated comprehensively with a view to holistic management. Physicians should be encouraged to take a positive attitude to the treatment outcomes for IBS patients.
키워드
Asia; Constipation; Diarrhea; Intestines; Irritable bowel syndrome
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