C형 간염 산모로부터 출생한 영아에서 C형 간염 Virus의 수직 전파 1례
A Case of Vertical Transmission of Hepatitis C Virus in an Infant of a Mother Who had Hepatitis C during Pregnancy
오상현, 문경래, 박상기, 양은석, 김국환,
소속 상세정보
오상현 ( Oh Sang-Hyun )
조선대학교 의과대학 소아과학교실
문경래 ( Moon Kyung-Rye )
조선대학교 의과대학 소아과학교실
박상기 ( Park Sang-Kee )
조선대학교 의과대학 소아과학교실
양은석 ( Yang Eun-Seok )
조선대학교 의과대학 소아과학교실
김국환 ( Kim kuk-Hwan )
조선대학교 의과대학 소아과학교실
KMID : 0816119990020010109
Abstract
저자들은 C형 간염이 있던 어머니에서 태어난 1
개월된 영아에서 HCV의 수직전파 1례를 경험하였
기에 보고하는 바이다.
Hepatitis C virus (HCV) has been identified as an important cause of posttransfusion
hepatitis, but vertical transmission of chronic infected HCV RNA positive mothers has
been documented in some cases. The reports of the risk of perinatal infection have been
widely varied in the literature. The authors experienced one case of vertical transmission
of HCV in an infant of a mother who had hepatitis C during pregnancy. At admission,
HCV RNA (+), Ig G anti HCV (+) and Ig M anti HCV (+) were found in the mother
Also at admission, HCV RNA (+), Ig G anti HCV (+), Ig M anti HCV (+), elevation of
liver aminotransferase level and hepatosplenomegaly on ultrasonography were found in
the baby on day 31. HCV RNA (-), Ig M anti HVC (-) and normal of liver
aminotransferase level were noted on day 250 in the serum of the infant. We used
reverse transcriptase polymerase chain reaction (RT-PCR) technique to find a very small
amount of HCV RNA in the serum. All the findings suggest vertical transmission of
HCV RNA from mother to infant during 3rd trimester of pregnancy.
키워드
Hepatitis C virus; Vertical transmission; Reverse transcriptase polymerase chain reaction;
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