Çе¿±â Àü Á¤»ó ¾Æµ¿ÀÇ Helicobacter pylori °¨¿°·ü¿¡ ´ëÇÑ ¿¬±¸
Seroepidemiology of H. pylori Infection in Normal Preschool Children
ÃÖ¿¬È£, ¼Á¤±â, ±èÀÇÁ¾,
¼Ò¼Ó »ó¼¼Á¤º¸
ÃÖ¿¬È£ ( Choi Yon-Ho )
¼¿ï´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
¼Á¤±â ( Seo Jeong-Kee )
¼¿ï´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
±èÀÇÁ¾ ( Kim Eui-Chong )
¼¿ï´ëÇб³ ÀÇ°ú´ëÇÐ ÀÓ»óº´¸®Çб³½Ç
KMID : 0816119990020020147
Abstract
¸ñÀû : H. pylori °¨¿°·üÀº »ýÈ°¼öÁØ°ú ¹ÐÁ¢ÇÑ °ü°è°¡ ÀÖ¾î °æÁ¦ÀûÀ¸·Î ¾î·Á¿ï¼ö·Ï °¨¿°·ü
ÀÌ ³ô¾ÆÁö¸ç »çȸ»ýÈ°À» ÇÏ¸é¼ ³ªÀÌ°¡ Áõ°¡ÇÔ¿¡ µû¶ó °°ÀÌ ¿Ã¶ó°£´Ù. ¼Ò¾Æ¿¡ ÀÖ¾î¼ ¼±Áø
±¹¿¡¼´Â 5% ¹Ì¸¸ÀÇ °¨¿°·üÀ» º¸ÀÌ°í ÀÖ°í ¿ì¸®³ª¶ó¿¡¼´Â 6¼¼¿¡¼ 15¼¼±îÁöÀÇ Á¤»ó¾Æµ¿¿¡
16.5%ÀÇ °¨¿°·üÀÌ º¸°í µÈ ¹Ù ÀÖ´Ù. ºÎ¸ð¿¬·ÉÀÇ °¨¿°·üÀÌ ³ôÀº ¿ì¸®³ª¶ó¿¡¼ 5¼¼ ÀÌÇÏ Á¤»ó
¾Æµ¿¿¡¼ÀÇ H. pylori °¨¿°·üÀº Ç÷¾×äÃë µîÀÇ ¾î·Á¿òÀ¸·Î ÇöÀç±îÁö °ÅÀÇ Á¶»çµÇ¾î ÀÖÁö ¾Ê
¾Æ H. pylori ƯÀÌ IgGÇ×ü°Ë»ç¸¦ ÀÌ¿ë, H. pyloriÄ¡ °¨¿°·üÀ» ¾Ë¾Æº¸°íÀÚ ÇÏ¿´´Ù.
¹æ¹ý : 1995³â ¼¿ï½Ã³» 3°÷ÀÇ ¾î¸°ÀÌÁýÀ» ¹æ¹®ÇÏ¿© 2¼¼¿¡¼ 5¼¼±îÁöÀÇ 220¸í(2¼¼ 24¸í, 3
¼¼ 54¸í, 4¼¼ 95¸í, 5¼¼ 47¸í)¿¡ ´ëÇÏ¿© Ç÷¾×À» äÃëÇÏ°í ELISA¸¦ ÀÌ¿ëÇÑ IgG GAP test·Î
H. pyloriÀÇ °¨¿°·üÀ» Á¶»çÇÏ¿´´Ù.
°á°ú :
1) ÃÑ 220¸íÁß ¾ç¼ºÀº 2¼¼ 1¸í, 3¼¼ 2¸í, 4¼¼ 1¸í, 5¼¼ 1¸íÀÇ ÃÑ 5¸íÀ¸·Î ¾ç¼º·üÀº 2.3%¿´
´Ù.
2) ¾à¾ç¼º(equivocally probable positive)Àº 2¼¼ 3¸í, 3¼¼ 3¸í, 4¼¼ 4¸í, 5¼¼ 3¸íÀÇ ÃÑ 13¸í
À¸·Î 220¸íÁß 5.9%¿´´Ù
°á·Ð : ¿ì¸®³ª¶ó 2¼¼¿¡¼ 5¼¼±îÁöÀÇ Á¤»ó¾Æµ¿¿¡ ÀÖ¾î¼ H. pyloriÀÌ °¨¿°·üÀº 2.3¡8.2%·Î
»ý°¢µÇ¾îÁö¸ç ¼±Áø±¹¿¡ ºñ±³ÇÏ¸é ¾ÆÁ÷µµ ³ôÀº ¼öÄ¡·Î ÇâÈÄ °¡Á·³» °¨¿° µî Áý´Ü°¨¿°°ú »çȸ
°æÁ¦Àû ȯ°æÀÇ º¯È¿¡ µû¸¥ °¨¿°·üÀÇ ÃßÀÌ¿¡ ´ëÇØ Áö¼ÓÀûÀÎ ¿¬±¸°¡ ÇÊ¿äÇÒ °ÍÀ¸·Î º»´Ù.
Purpose : The aim of this study was to evaluate the prevalence of H. pylori infection
in normal preschool children.
Methods : Study population consisted of 220 preschool children aged 2 to 5 years in
Seoul, Korea. We measured H. pylori specific IgG antibody using the GAP test IgG kit,
and samples with concentrations greater than 20 U/§¢ were considered positive.
Results : Of the 220 children, 5 (2.3%) were positive, and thirteen (5.9%) of 220 were
equivocally probable positive.
Conclusion : The positive rate of H. pylori infection detected by specific IgG antibody
in normal preschool children aged 2 to 5 years was approximately 2.3% to 8.2%. This
prevalence rate is still high, compared to that of the West. A better knowledge of the
transmission of H. pylori is crucial to formulate recommendations for lowering the rate.
Å°¿öµå
Helicobacter pylori; Prevalence; Preschool children; IgG GAP test;
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