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Ç×¾Ï È­Çпä¹ý ÁßÀÎ ¼Ò¾Æ¾Ï ȯÀÚÀÇ ¿µ¾ç Æò°¡ ¹× ½ÄÀÌ °ü¸® Nutritional Assessment and Dietary Management during Anti-Cancer Chemotherapy in Pediatric Oncology Patients

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Abstract

¸ñÀû : ¼Ò¾Æ¾Ï ȯÀÚµéÀ» ´ë»óÀ¸·Î Ç×¾ÏÄ¡·á ÀüÈÄÀÇ ¿µ¾ç»óŸ¦ Æò°¡ÇÏ°í, Ç×¾Ï Ä¡·á±â°£
Áß ¹ß»ýÇÏ´Â ½Ä¿åºÎÁø½Ã¿¡ ¼·Ãë·® ¹× ±âÈ£ ½ÄÇ°À» Á¶»çÇÔÀ¸·Î½á ÇâÈÄ À̵é ȯÀÚÀÇ º¸´Ù ³ª
Àº ¿µ¾ç°ü¸®¸¦ À§ÇÑ ÁöħÀ» ¸¶·ÃÇÏ°íÀÚ º» ¿¬±¸¸¦ ½ÃÇàÇÏ¿´´Ù.

¹æ¹ý : 1996³â 1¿ùºÎÅÍ 1998³â 12¿ù±îÁö µ¿¾Æ´ëÇб³º´¿ø ¼Ò¾Æ°ú¿¡¼­ ¹éÇ÷º´ ¹× ¼Ò¾Æ¾ÏÀ¸
·Î Áø´Ü¹Þ°í Ç×¾Ï Ä¡·á¸¦ ½ÃÀÛÇϴ ȯÀÚ 20¸íÀ» ´ë»óÀ¸·Î ÇÏ¿´´Ù. À̵é ȯÀÚÀÇ Ç×¾Ï Ä¡·á
Àü°ú 21ÀÏ ÈÄÀÇ ¿µ¾ç»óÅ Æò°¡¸¦ À§ÇÏ¿© ÀÎü °èÃø°ú »ýÈ­ÇÐÀû °Ë»ç(ÃÑ ´Ü¹éÁú, ¾ËºÎ¹Î,
AST, ALT, BUN, creatinine)¸¦ ½ÃÇàÇÏ¿´´Ù. Ç×¾Ï Ä¡·á ±â°£Áß ½Ä¿åÀúÇÏ ±â°£°ú ¿øÀÎ ¹× Æò
¼Ò¿¡ ¼±È£ÇÏ´Â ½ÄÇ°°ú Ä¡·á ÈÄ¿¡ ¼±È£ÇÏ´Â ½ÄÇ°¿¡ °üÇÑ ±âÈ£µµ¸¦ ¼³¹® Á¶»çÇÏ¿´´Ù.

°á°ú :
1) ´ë»ó ȯÀÚ´Â ³²¾Æ 10¸í, ¿©¾Æ 10¸íÀ̾úÀ¸¸ç, ¿¬·ÉÀº 3¼¼¿¡¼­ 15¼¼·Î Á¤Áß ¿¬·ÉÀÌ 6¼¼ÀÌ
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¾¾ Á¾¾ç 2¸í, ³úÁ¾¾ç 2¸í, Ⱦ¹®±Ù À°Á¾ 1¸íÀ̾ú´Ù.
2) Ç×¾Ï Ä¡·á¸¦ ¹Þ´Â µ¿¾È üÁß °¨¼Ò°¡ ÀÖ¾ú´ø °æ¿ì°¡ 8¸í (40%), üÁß Áõ°¡°¡ ÀÖ¾ú´ø °æ
¿ì°¡ 5¸í(25%), üÁßÀÇ º¯È­°¡ ¾ø¾ú´ø °æ¿ì°¡ 7¸í (35%)À̾ú´Ù.
3) Ç×¾Ï Ä¡·á¸¦ ¹Þ´Â µ¿¾È ½ÇÁ¦ ½Ä»ç ¼·Ãë·®Àº 1ÀÏ Æò±Õ 450 §» (310¡­600 §»)À̾ú´Ù.
4) Ç×¾Ï Ä¡·á ½ÃÀÛ ´ç½Ã Ç÷û ¾ËºÎ¹ÎÀº 3.1¡­4.4g/dLÀÇ ºÐÆ÷·Î Á¤»óº¸´Ù ³·Àº ¹üÀ§¿¡ ÀÖ
¾úÀ¸¸ç Ç×¾Ï Ä¡·á 21ÀÏ°´Â 2.7¡­5.0 g/dL·Î¼­ Åë°èÀû Â÷ÀÌ´Â º¸ÀÌÁö ¾Ê¾Ò´Ù. Ç÷û ALT´Â
Ç×¾Ï Ä¡·áÀüº¸´Ù ÀǹÌÀÖ°Ô Áõ°¡ÇÏ¿´À¸³ª(p<0.05),Ç÷û AST, BUN, creatinine, ÃÑ ´Ü¹éÁúÀº
ÀÇ¹Ì ÀÖ´Â º¯È­°¡ ¾ø¾ú´Ù.
5) Ç×¾Ï Ä¡·á±â°£ µ¿¾È ½Ä¿åÀúÇÏÀÇ ¿øÀÎÀ¸·Î¼­´Â ±¸Åä°¡ 37%·Î °¡Àå ¸¹¾ÒÀ¸¸ç ¸Þ½º²¨¿ò,
¾Ã±â °ï¶õÇÔ, ¿¬ÇÏ °ï¶õ, À½½Ä Çø¿À ¼øÀ̾ú´Ù.
6) ½Ä¿å ÀúÇϸ¦ È£¼ÒÇÒ ¶§ ¸ÔÀº ½ÄÇ°À¸·Î¼­ ȺÁ×, Àüº¹Á× µîÀÇ Á× Á¾·ù¸¦ °¡Àå ¸¹ÀÌ ¸Ô¾ú
°í, °õ±¹, Àå¾î µîÀÇ º¸¾ç½ÄÀ» ±× ´ÙÀ½À¸·Î ¼·ÃëÇÏ¿´À¸¸ç ÀνºÅÏÆ® ½ÄÇ°µµ ¼·ÃëÇÏ¿´´Ù.
7) Ç×¾Ï Ä¡·á±â°£ µ¿¾È ź»ê À½·á¸¦ °¡Àå ÁÁ¾ÆÇÏ¿´°í, ¸Ê°í ÀÚ±ØÀûÀÎ ½ÄÇ°À» ÁÁ¾ÆÇÏ´Â °Í
À¸·Î ³ªÅ¸³µÀ¸¸ç, ½È¾îÇÏ´Â ½ÄÇ°À¸·Î´Â Æò¼Ò ½È¾îÇÏ´Â ½ÄÇ°°ú ¸¶Âù°¡Áö·Î ¾ßä·ù·Î ³ªÅ¸³µ
´Ù.

°á·Ð : Ç×¾Ï È­Çпä¹ýÀ» ¹Þ°í ÀÖ´Â ¼Ò¾ÆµéÀº ¼Ò¸ð¼º ÁúȯÀ¸·Î ÀÎÇØ ¿µ¾ç»óÅ°¡ ´õ¿í ³ªºü
Áö±â ½¬¿ì¹Ç·Î Ç×¾Ï Ä¡·á¸¦ ¹Þ´Â ±â°£µ¿¾È º¸´Ù Àû±ØÀûÀÌ°í ü°èÀûÀΠȯÀÚÀÇ ½Ä»ç ¼·Ãë·®
Á¶»ç ¹× ȯÀÚ »óÅÂ¿Í ±âÈ£¿¡ ÀûÇÕÇÑ ÇüÅÂÀÇ ½Ä»çÁ¾·ù °³¹ßÀÌ ÇÊ¿äÇϸç, ȯÀÚ³ª º¸È£Àڵ鿡
°Ôµµ ÀûÀýÇÑ ½Ä»ç Á¾·ù ¹× ½Ä»ç¿ä·ÉÀ» ±³À°, È«º¸ÇÏ¿© ȯÀÚÀÇ ½Ä»ç ¼·Ãë·® Áõ°¡¸¦ ÅëÇÑ ¿µ
¾ç »óÅ °³¼±ÀÌ ÀÌ·ç¾îÁöµµ·Ï ÇØ¾ß ÇÏ°Ú´Ù.

Purpose : We assessed the nutritional status and the alterations of oral diets during
anti-cancer chemotherapy in pediatric oncology patients.

Methods : Twenty children with malignancy were evaluated from day 0 until day 21
of post-chemotherapy. Nutritional status was assessed by body weight and biochemical
parameters. The amount and calories of oral diets were assessed and food preference
before and during chemotherapy were analysed by questionnelle.

Results : 1) The underlying diseases of 20 patients were 11 acute lymphoblastic
lekemia, 2 non-Hodgkin¡¯s lymphoma, 2 Langerhans cell histiocytosis, 2 Wilm¡¯s tumor, 2
brain tumor, 1 rhabdomyosarcoma. 2) There were weight loss during chemotherapy in 8
patients (40.0%), weigh gain in 5 patients (25.0%), and no significant changes in 7
patients (35.0%). 3) Biochemical parameters showed no significant interval changes
during chemotherapy except elevation of serum ALT level. 4) The daily caloric intakes
of oral diets during chemotherapy were 310¡­600 §» which was much lower than
average of daily recommended calory for Korean children. 5) The most favorate food
was altered by chemotherapy, from meats to carbonated beverages and unfavorate food
was not altered as vegetables.

Conclusion : The periodic assessment of nutritional status and dietary supplements
according to preferred foods of patients will be required for the optimal nutrition care in
cancer patients.

Å°¿öµå

Nutrition; Diet; Pediatric malignancy; Anti-cancer chemotherapy;

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