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Failure to Thrive¸¦ ÁÖ¼Ò·Î ³»¿øÇÑ È¯¾ÆµéÀÇ ÀÓ»ó»ó Clinical Manifestation of Children with Failure to Thrive

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¹®Á¤Èñ, ¹é³²¼±, ±èÁö¿µ,
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¹®Á¤Èñ ( Moon Jeong-Hee ) 
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¹é³²¼± ( Beck Nam-Sun ) 
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±èÁö¿µ ( Kim Ji-Young ) 
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Abstract

¸ñÀû : ¿¬±¸ÀÚµéÀº »ï¼ºÀÇ·á¿ø ¼Ò¾Æ°ú¿¡ »ó±â Áõ»óÀ¸·Î ³»¿øÇÑ È¯¾ÆÀÇ ÀÓ»ó»óÀ» ¾Ë¾Æº¸°í
ÀÚ º» ¿¬±¸¸¦ ½ÃÇàÇÏ¿´´Ù.

¹æ¹ý : 1997³â 3¿ùºÎÅÍ 1999³â 7¿ù±îÁö failure to thrive¸¦ ÁÖ¼Ò·Î »ï¼ºÀÇ·á¿ø ¼Ò¾Æ°ú ¿µ¾ç
Å©¸®´ÐÀ» ¹æ¹®ÇÑ 16¼¼ ÀÌÇÏÀÇ ¿µ¾Æ ¹× ¼Ò¾Æ ȯÀÚ 74¸íÀ» ´ë»óÀ¸·Î ÈÄÇâÀûÀÎ ¹æ¹ýÀ¸·Î º´·Ï
Áö °íÂûÀ» ÅëÇÏ¿© ÀÓ»ó »óÀ» ¾Ë¾Æº¸¾Ò´Ù. ¿Ü·¡¸¦ ³»¿øÇÏ¿´À» ¶§ ȯ¾ÆÀÇ Ãâ»ýüÁß, üÁú¼º ¼º
ÀåÁö¿¬ÀÇ °¡Á··ÂÀ» Æ÷ÇÔÇÏ´Â º´·ÂûÃë¿Í ½Åü°Ë»ç·Î ¼³¸íÀÌ µÇÁö ¾Ê´Â °æ¿ì´Â ÈäºÎ ¹æ»ç¼±
ÃÔ¿µ, °£ ±â´É °Ë»ç, ÀüÇØÁú °Ë»ç, ½ÅÀå±â´É °Ë»ç, Ç÷¾× °Ë»ç, ¿äħ»ç¸¦ Æ÷ÇÔÇÏ´Â ¼Òº¯°Ë»ç¸¦
½ÃÇàÇÏ¿´°í ÇÊ¿äÇÑ °æ¿ì ³úÆÄ°Ë»ç, Brain MRI, °ñ ¿¬·É µîÀ» ÃøÁ¤ÇÏ¿´´Ù. ¶ÇÇÑ ¿µ¾ç»çÀÇ µµ
¿òÀ» ¾ò¾î ÇöÀç ¼·ÃëÇÏ°í ÀÖ´Â À½½ÄÀÇ ¿­·®À» ºÐ¼®ÇÏ¿´´Ù.

°á°ú : 1) 74¸íÀÇ È¯¾ÆÀÇ º´·ÏÁö °íÂûÀÌ °¡´ÉÇÏ¿´°í ÀÌÁß ³²¾Æ°¡ 43¸íÀ̾úÀ¸¸ç ³ªÀÌ´Â 1°³
¿ù¿¡¼­ 13³â 1°³¿ù(Æò±Õ: 3.3¡¾3.7¼¼)À̾ú´Ù. 2) ÀüüÀûÀ¸·Î ¿øÀÎÀ» ÃßÁ¤ÇÒ ¼ö ÀÖ¾ú´ø ÃÑ 69
·Ê Áß »ý¸®Àû failure to thrive¿¡¼­´Â °¡Á·¼º Àú½ÅÀåÁõ, IUGR, üÁú¼º ¼ºÀåÁö¿¬,
Idiosyncrasy, ¹Ì¼÷¾Æ ¼ø ÀÌ¿´°í º´Àû ¿øÀÎÀÇ °æ¿ì ³ªÀÌ¿Í °ü°è¾øÀÌ ÁßÃß ½Å°æ°èÁúȯ, À§Àå
°ü Áúȯ, ¾Ë·¹¸£±â Áúȯ ¼ø À̾ú´Ù. 3) 3¼¼ ¹Ì¸¸ÀÇ ±º¿¡¼­´Â ¿øÀÎÀ» ÃßÁ¤ÇÒ ¼ö ÀÖ¾ú´ø ÃÑ 41
·Ê Áß 19·Ê(46.3%)°¡ »ý¸®Àû ¿øÀÎÀ̾ú°í IUGR°ú °¡Á·¼º Àú½ÅÀåÁõÀÌ °¡Àå ¸¹¾Ò´Ù. 4) 3¼¼
ÀÌ»óÀÇ ±º¿¡¼­´Â ¿øÀÎÀ» ÃßÁ¤ÇÒ ¼ö ÀÖ¾ú´ø 28·ÊÀÇ È¯¾Æ Áß 14·Ê(50%)¿¡¼­ »ý¸®Àû ¿øÀÎÀ¸·Î
°¡Á·¼º Àú½ÅÀåÁõ, üÁú¼º ¼ºÀåÁö¿¬, IUGR ¼ø À̾ú´Ù. Æò±Õ ¼·Ãë¿­·®Àº ÇÏ·ç ±ÇÀå·®ÀÇ 76.2%
¿´´Ù. üÁú¼º ¼ºÀåÁö¿¬°ú IUGR, Idiosyncrasy, º´Àû failure to thrive´Â Æò±Õ ¼·Ãë¿­·®ÀÌ Àû
Àº °æÇâÀ» º¸¿´°í, ¹Ì¼÷¾Æ´Â ºñ±³Àû Á¤»óÀûÀÎ ¼Ò°ßÀ» º¸¿´À¸¸ç °¡Á·¼º Àú½ÅÀåÁõÀÇ °æ¿ì ¿­
·® °ø±ÞÀÌ °í·ç ºÐÆ÷µÇ´Â °æÇâÀ» º¸¿´´Ù. 5) ½ÅüÇüÀº »ý¸®Àû failure to thriveÀÇ ¿øÀÎ Áß ¹Ì
¼÷¾Æ, IUGR°ú º´ÀûÀÎ failure to thrive¿¡¼­´Â ½ÅÀå°ú üÁß ¸ðµÎ °¨¼ÒµÇ¾î ÀÖ´Â ÇüÀÌ °¡Àå
¸¹¾Ò°í, üÁú¼º ¼ºÀåÁö¿¬°ú °¡Á·¼º Àú½ÅÀåÁõ¿¡¼­´Â ½ÅÀåÀº Á¤»óÀ̳ª üÁßÀº °¨¼ÒµÇ¾î ÀÖ´Â
ÇüÀÌ ¸¹¾Ò´Ù.

°á·Ð : Failure to thrive´Â 3¼¼ ¹Ì¸¸¿¡¼­´Â IUGR ¹× °¡Á·¼º Àú½ÅÀåÁõ µîÀÌ failure to
thriveÀÇ °¡Àå ÈçÇÑ ¿øÀÎÀÌ°í 3¼¼ À̻󿡼­´Â °¡Á·¼º Àú½ÅÀåÁõ°ú üÁú¼º ¼ºÀåÁö¿¬ µî À¯Àü
ȯ°æÀÌ °¡Àå ÈçÇÑ ¿øÀÎÀÌ´Ù. º´ÀûÀÎ failure to thriveÀÇ ¿øÀÎÀº ³ªÀÌ¿Í °ü°è¾øÀÌ ÁßÃß ½Å°æ
°èÁúȯ, À§Àå°ü ÁúȯÀÌ °¡Àå ÈçÇÑ ¿øÀÎÀÌ´Ù. ¿µ¡¤À¯¾Æ¸¦ Æ÷ÇÔÇÏ´Â ¼Ò¾Æ¿¡¼­ÀÇ failure to
thriveÀÇ ¿øÀÎÀº ´ë°³ Ä¡·á°¡ ÇÊ¿äÇÏÁö ¾Ê´Â »ý¸®ÀûÀÎ ¿øÀÎÀÌ ¸¹°í ¿ÏÀüÇÑ º´·ÂûÃë ¹× ½Å
ü °Ë»ç¸¸À¸·Îµµ Áø´ÜÀÌ °¡´ÉÇϹǷΠÁ¶±â Áø´Ü ÈÄ ÀûÀýÇÑ ¿µ¾çÆò°¡´Â Áß¿äÇϸ®¶ó »ý°¢µÈ´Ù.

Purpose : This study was to investigate the clinical manifestations of FTT in children.

Methods : From March 1997 to July 1999, clinical observations were made on patients
with FTT who had visited to Samsung Medical Center. Detailed histories and through
physical examinations were taken, and when suspected organic FTT, basic laboratory
studies were done.

Results : Upon the review of medical records, we investigated the clinical
manifestations of 74 children, aged 1 month and 13 year 1 month. The causes of FTT
were composed of either physiologic (47.8%) or pathologic (52.2%) ones. Among the
physiologic FTT, were there familial short stature (FSS, 14.5%), intrauterine growth
retardation (IUGR, 14.5%), constitutional growth delay (CGD, 11.6%), idiosyncrasy and
prematurity. Among pathologic causes, neurologic disorders (20%) are the most common
causes of FTT, and then follow by GI (13.4%), allergic and infectious disorders in
decreasing order. The data showed that average caloric intake in patients with FTT
was 76.2% of recommended amount. FTT patients with CGD, IUGR, and idiosyncrasy
had tendency to take small foods. The FTT children with prematurity, IUGR and
pathologic FTT, were short and thin for their ages. However FTT children with CGD
and FSS had tendency to be thin with relatively normal heights for their ages, in
comparison with those of the children with prematurity, IUGR and pathologic FTT.

Conclusion : The diagnosis of FTT was easily obtained with simple and through
medical history, physical examination, and minimal laboratory tests. In this study,
organic FTT was more prevalent than physiologic one. This results indicate that early
intervention is mandatory, because children may develop significant long-term sequelae
from nutritional deficiency.

Å°¿öµå

Failure to thrive; Familial short stature; Constitutional growth delay; Idiosyncray; Intrauterin growth retardation;

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