È£»ê±¸ Áõ°¡ÁõÀ» µ¿¹ÝÇÑ °Å´ë¼¼Æ÷¹ÙÀÌ·¯½º °¨¿° ¼Ò¾Æ Menetrier º´ 1·Ê
Cytomegalovirus-induced Childhood Menetrier¡¯s Disease with Peripheral Eosinophilia
ÃÖ¿øÁ¤, ÀÌÈñÁ¤, ȲÁøº¹, ¿ÀÈƱÔ, À̺¸¿µ,
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ÃÖ¿øÁ¤ ( Choi Won-Joung )
°è¸í´ëÇб³ ÀÇ°ú´ëÇÐ È¿¼º¾Æµ¿º´¿ø ¼Ò¾Æ°ú
ÀÌÈñÁ¤ ( Lee Hee-Jung )
°è¸í´ëÇб³ ÀÇ°ú´ëÇÐ Áø´Ü¹æ»ç¼±Çб³½Ç
ȲÁøº¹ ( Hwang Jin-Bok )
°è¸í´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
¿ÀÈÆ±Ô ( Oh Hoon-Kyu )
°è¸í´ëÇб³ ÀÇ°ú´ëÇÐ º´¸®Çб³½Ç
À̺¸¿µ ( Lee Bo-Young )
°è¸í´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
KMID : 0816120040070010087
Abstract
ÀúÀÚµéÀº º¹Åë°ú ±¸Åä¿¡ µ¿¹ÝµÈ Àü½Å ºÎÁ¾À» ÁÖ¼Ò·Î ³»¿øÇÏ¿© Àú¾ËºÎ¹ÎÇ÷Áõ°ú ¸»ÃÊÇ÷¾× È£»ê±¸Áõ°¡ÁõÀÇ ÀÓ»ó ¼Ò°ßÀ¸·Î ´Ü¹é ¼Ò½Ç¼º À§ÀåÁõÀ» µ¿¹ÝÇÑ È£»ê±¸¼º À§Àå°ü¿°À¸·Î ÀǽɵǾúÀ¸³ª, ³»½Ã°æ°Ë»ç ¼Ò°ß, Á¶Á÷ ¼Ò°ß, ¹æ»ç¼± ¼Ò°ß°ú ÀúÀý·Î ÁÁ¾ÆÁö´Â ÀÏ°ú¼º ÀÓ»ó °æ°ú µîÀ» Á¾ÇÕÇÏ¿© ¸»ÃÊÇ÷¾×ÀÇ È£»ê±¸ Áõ°¡Áõ°ú Á¶Á÷ ³»¿¡¼ È£»ê±¸ÀÇ ½ÉÇÑ Ä§À±À» º¸ÀÎ CMV °¨¿° ¼Ò¾Æ Menetrierº´ 1·Ê¸¦ º¸°íÇÏ°íÀÚ ÇÑ´Ù. CMV °¨¿°°ú °ü·ÃµÈ ¼Ò¾Æ Menetrierº´ÀÇ Æ¯Â¡ÀûÀÎ ÀÓ»ó Áõ»ó°ú ¼Ò°ßÀ» ¿°µÎ¿¡ µÎ¾î¾ß Çϸç, ÇâÈÄ CMV °¨¿°°ú ¸»ÃÊ Ç÷¾× È£»ê±¸Áõ°¡Áõ°ú Á¶Á÷³» È£»ê±¸ ħÀ±ÀÇ °ü·Ã¼º¿¡ ´ëÇÏ¿© ÀÓ»óÀû Çؼ®ÀÌ ÇÊ¿äÇϸ®¶ó ÆǴܵȴÙ.
Herein, the case of a 5-year-old boy with cytomegalovirus-induced Menetrier¡¯s disease, with peripheral eosinophilia, presenting with abdominal pain and vomiting, followed by generalized edema, is reported. The initial laboratory findings, hypoalbuminemia and peripheral eosinophilia were noted, with no evidence of renal, hepatic, cardiac or allergic diseases. Gastrofiberscopy was performed under the suspicion of eosinophilic gastroenteritis with protein losing gastropathy. The gastrofiberscopy showed the characteristic features of giant hypertrophy of the gastric rugae, with large quantities of adherent gelatinous material on the gastric fundus and body. The histological findings revealed foveolar hyperplasia, compatible with Menetrier¡¯s disease, with massive eosinophilic infiltrations. The presence of cytomegalovirus infection was identified by serology and confirmed by urine PCR. His symptoms, gastrofiberscopic findings and peripheral eosinophilia resolved spontaneously, and he has remained well for 10 months.
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Menetrier`s disease;Cytomegalovirus;Eosinophilia
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