소아에서 발생한 위장관 간질 종양 1예
A Case of Gastrointestinal Stromal Tumor in a Child
윤경빈, 설지영, 강대영, 김재영, 유재홍,
소속 상세정보
윤경빈 ( Yun Kyung-Bin )
충남대학교 의과대학 소아과학교실
설지영 ( Sul Ji-Young )
충남대학교 의과대학 외과학교실
강대영 ( Kang Dae-Young )
충남대학교병원 병리과
김재영 ( Kim Jae-Young )
충남대학교 의과대학 소아과학교실
유재홍 ( Yu Jae-Hong )
충남대학교 의과대학 소아과학교실
KMID : 0816120070100010071
Abstract
Gastrointestinal stromal tumors (GISTs) are the most common primary mesenchymal tumors of the digestive tract. They have been commonly observed in adults but have been rarely described in children. They arise typically from the intestinal wall and rarely in the mesentery, omentum, or retroperitoneum. GISTs originate from the interstitial cell of Cajal and are characterized by overexpression of the receptor tyrosine kinase c-kit. Up to 94% of these tumors express the CD117 on immunohistochemical stain. Surgery is the main modality of treatment for primary resectable GIST. Completely resectable GIST with low risk has excellent prognosis after primary surgical intervention, with over 90% of the 5-year survival. We report a case of 10-year-old girl presenting with an upper gastrointestinal bleeding caused by gastrointestinal stromal tumor.
키워드
Gastrointestinal stromal tumor (GISTs);Interstitial cell of Cajal;Receptor tyrosine Kinase c-kit;CD117;Immunohistochemical stain
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