Noroviruses: Recent Updates
정주영,
소속 상세정보
정주영 ( Chung Ju-Young )
인제대학교 의과대학 상계백병원 소아청소년과
KMID : 0816120120150010001
Abstract
Noroviruses (NoVs) are one major etiologic agent in acute gastroenteritis (AGE) in all ages and are the primary cause of food-borne gastroenteritis worldwide. GII-4 NoVs has predominated since 1990s, and novel recombinant strains have been reported worldwide. Researchers face difficulties in making vaccines and therapeutic agents against NoVs due to the lack of cell culture and animal-model systems and the rapid emergence of novel variant strains. Recently, a randomized clinical trial for intranasal NoVs vaccine has been reported, which casts a light in the way of vaccine production. This review discusses the recent findings on the structure, immunity, and vaccination of NoVs.
키워드
Norovirus; Gastroenteritis; Children; Vaccine
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