A Pediatric Case of Toxic Hepatitis Induced by Hovenia Dulcis
김윤지, Ryu Seung-Lok, 심재원, 김덕수, 심정연, 박문수, 정혜림,
소속 상세정보
김윤지 ( Kim Yun-Ji )
성균관대학교 의과대학 소아청소년과학교실
( Ryu Seung-Lok )
성균관대학교 의과대학 소아청소년과학교실
심재원 ( Shim Jae-Won )
성균관대학교 의과대학 소아청소년과학교실
김덕수 ( Kim Duk-Soo )
성균관대학교 의과대학 소아청소년과학교실
심정연 ( Shim Jung-Yeon )
성균관대학교 의과대학 소아청소년과학교실
박문수 ( Park Moon-Soo )
성균관대학교 의과대학 소아청소년과학교실
정혜림 ( Jung Hye-Lim )
성균관대학교 의과대학 소아청소년과학교실
KMID : 0816120120150020111
Abstract
Toxic hepatitis is a rare but devastating disease in children. Herbs are widely used in oriental medicine to treat various symptoms in Korea, however, several herbs have been reported to induce liver injury. We report a case of toxic hepatitis induced by Hovenia dulcis in a 3-year-old boy. He complained of nausea, abdominal discomfort, and jaundice. The patient had consumed water boiled with hovenia dulcis for about 1 year prior to presentation. A diagnosis of toxic hepatitis was made based on his history, laboratory data, viral markers, ultrasonography, and biopsied liver tissue. We administered supportive management for acute fulminant hepatitis but his symptoms and liver function progressed. He was transferred to another hospital for further evaluation and consideration for liver transplantation. Because acute liver failure due to herbs or dietary supplement taken for a long time is often fetal, it is important to make early diagnosis and stop taking the drug as soon as drug induced liver injury is suspected.
키워드
Toxic hepatitis; Hovenia dulcis; Children
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