Current Status of Intestinal Failure and Intestinal Transplantation
고재성,
소속 상세정보
고재성 ( Ko Jae-Sung )
Seoul National University College of Medicine Department of Pediatrics
KMID : 0816120120150030127
Abstract
Pediatric intestinal failure occurs secondary to short bowel syndrome, motility disorders, or malabsorption. The establishment of an intestinal rehabilitation program and the introduction of innovative surgical and medical treatments, such as the serial transverse enteroplasty procedure and omega-3-containing lipid emulsions, have been major advances in the treatment of intestinal failure. Intestinal transplantation is now established as a therapeutic modality in selected children with irreversible intestinal failure. The improved short to intermediate term survival of intestinal transplant recipients in the last decade can be attributed to immunosuppression with a lymphocyte-depleting agent, control of acute cellular rejection, and comprehensive infection control with careful monitoring of viral pathogens including cytomegalovirus and Epstein-Barr virus.
키워드
Intestinal failure; Short bowel syndrome; Intestinal transplantation; Child; Survival
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