Gut Microbiota in Inflammatory Bowel Disease
심정옥,
소속 상세정보
심정옥 ( Shim Jung-Ok )
Korea University College of Medicine Department of Pediatrics
KMID : 0816120130160010017
Abstract
The gut mucosal barrier plays an important role in maintaining a delicate immune homeostasis. The pathogenesis of inflammatory bowel disease (IBD) is considered to involve a defective mucosal immunity along with a genetic predisposition. Recent views have suggested an excessive response to components of the gut microbiota in IBD. A condition of "dysbiosis", with alterations of the gut microbial composition, has been observed in patients with IBD. In this article, the author review recent studies of gut microbiota in IBD, particularly the importance of the gut microbiota in the pathogenesis of pediatric IBD.
키워드
Microbiota;Inflammatory bowel diseases;Child
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