Monitoring and Safety of Azathioprine Therapy in Inflammatory Bowel Disease
김미진, 최연호,
소속 상세정보
김미진 ( Kim Mi-Jin )
Inje University College of Medicine Ilsanpaik Hospital Department of Pediatrics
최연호 ( Choe Yon-Ho )
Sungkyunkwan University School of Medicine Samsung Medical Center Department of Pediatrics
KMID : 0816120130160020065
Abstract
Azathioprine is the most common drug used to maintain clinical remission in inflammatory bowel disease. This drug is also important as a steroid-sparing agent in steroid-dependent and chronically active inflammatory bowel disease. Nevertheless, many questions remain concerning the optimal treatment regimens of azathioprine. The dose of azathioprine has to be reduced or the therapy has to be discontinued frequently because of drug-induced toxicity. In this review, we discuss monitoring of thiopurines, adverse events, malignant complications and how to use azathioprine safely and usefully.
키워드
Azathioprine;Inflammatory bowel diseases
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