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ºñ »ó¾÷¿ë 3Â÷¿ø Ä¡·á°èȹ½Ã½ºÅÛÀÎ PluncÀÇ ÀÓ»óÀû¿ë °¡´É¼º¿¡ ´ëÇÑ ¿¬±¸ A Study of a Non-commercial 3D Planning System, Plunc for Clinical Applicability

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Abstract

¸ñ Àû : ºñ »ó¾÷¿ë 3Â÷¿ø ÄÄÇ»ÅÍÄ¡·á°èȹ½Ã½ºÅÛÀÎ PluncÀÇ ±¸Ãà »ç·Ê¸¦ ¼Ò°³ÇÏ°í ÀÌÀÇ ÀÓ
»óÀû¿ë °¡´É¼º¿¡ ´ëÇÏ¿© °ËÁõÇÏ°íÀÚ ÇÑ´Ù.
´ë»ó ¹× ¹æ¹ý : ¹Ì±¹ North Carolina ´ëÇп¡¼­ °³¹ßµÈ 3Â÷¿ø Ä¡·á°èȹ½Ã½ºÅÛÀÎ PluncÀÇ
¼Ò½ºÄڵ带 Á¦°ø¹Þ¾Æ, PC¿ë UnixÀÎ Linux ȯ°æÀÇ Pentium Pro 200MHz(128MB RAM,
Millennium VGA)¿¡¼­ ¼³Ä¡ÇÏ¿´´Ù. º»°úÀÇ 6MV ±¤ÀÚ¼±(Siemens MXE 6740)¿¡ ´ëÇÑ Ãâ·Â
ÀÎÀÚ, ÃÖ´ë»ê¶õºñ, ÃÖ´ë»ê¶õÀÎÀÚ, ½û±âÀÇ ¸ð¾ç ¹× °¨¼âÀÎÀÚ µîÀÇ ºöµ¥ÀÌÅ͸¦ ÀÔ·ÂÇÑ ÈÄ, ÀϹÝ
ÀûÀÎ Ä¡·áÁ¶°ÇÀÎ l0Cm ±íÀÌÀÇ È¸ÀüÁß½ÉÁ¡¿¡¼­ÀÇ ½ÉºÎ¼±·®¹éºÐÀ², ¼±·®Ãø¸éµµ, oblique ÀÔ»ç
ºö ¹× °ø±â°£°Ý ÇÏ¿¡¼­ÀÇ ¼±·®°è»ê °á°ú¸¦ ¹°ÆÒÅè¿¡¼­ÀÇ ÃøÁ¤Ä¡¿Í ºñ±³, ºÐ¼®ÇÏ¿´´Ù.
°á °ú : Plunc´Â ¿ø·¡ CT ¿µ»óµ¥ÀÌÅ͸¦ ÀÌ¿ëÇÑ ¸ðÀÇÄ¡·á±â·Î½á °³¹ßµÇ¾î, ºö ¼³°è°¡ ¸Å¿ì
Æí¸®Çϵµ·Ï »ç¿ëÀÚ ÀÎÅÍÆäÀ̽º°¡ ±¸¼ºµÇ¾î ÀÖÀ¸¸ç, BEV, DRR ¹× ¿µ»óÇÕ¼º µîÀÇ ±â´ÉÀ» °®
Ãß°í ÀÖ´Ù. ¼±·® °è»êÀº 10ÃÊ Á¤µµ°¡ ¼Ò¿äµÇ´Â 3Â÷¿ø ¼±·®ºÐÆ÷³ª ¼±·®Ã¼ÀûÈ÷½ºÅä±×¶÷À» Á¦
¿ÜÇÏ°í´Â °ÅÀÇ ½Ç½Ã°£À¸·Î ½ÇÇàµÇ¾ú´Ù.
Plunc¿¡ ÀÇÇÑ ¼±·® °è»ê °ªÀ» ÃøÁ¤°ª°ú ºñ±³ÇÑ °á°ú, ½ÉºÎ¼±·®¹éºÐÀ²ÀÇ °æ¿ì, ¼±·®Áõ°¡¿µ
¿ªÀ» Á¦¿ÜÇÏ°í´Â 1%À̳»¿¡¼­ ÀÏÄ¡ÇÏ¿´´Ù. ¶ÇÇÑ, ¼±·®Ãø¸éµµÀÇ °æ¿ì, 5%°¡·®ÀÇ ¼±·®°¨¼Ò¸¦
³ªÅ¸³»´Â Ä¡·á¿µ¿ª Å©±â ¹ÛÀÇ Àú¼±·® ¿µ¿ªÀ» Á¦¿ÜÇÏ°í´Â 2% À̳»¿¡¼­ ÀÏÄ¡ÇÏ¿´´Ù. Oblique
ÀÔ»ç ºöÀÇ °æ¿ì, ºö Áß½ÉÃàÀ» Æ÷ÇÔÇÏ´Â Æò¸é»óÀÇ ¼±·®ºÐÆ÷°¡ ¼±·®ÀÌ 30% ÀÌÇÏÀÎ ¿µ¿ªÀ» Á¦
¿ÜÇÏ°í´Â ºñ±³Àû Àß ÀÏÄ¡ÇÏ¿´´Ù. °ø±â°£°ÝÀ» Åë°úÇÑ ºö¿¡ ´ëÇÑ ¼±·®Ãø¸éµµÀÇ ºñ±³ °á°ú, Áß
½É Ãà¿¡¼­ÀÇ ¼±·® °ª¿¡ ´ëÇØ 5%ÀÇ ¿ÀÂ÷¸¦ º¸¿´´Ù
°á ·Ð : PluncÀÇ ±¤ÀÚ¼±·®°è»êÀÇ Á¤¹Ðµµ´Â ÀϹÝÀûÀÎ Ä¡·áÁ¶°ÇÇÏ¿¡¼­ ¾à 2-5% ³»¿ÜÀÇ ¿À
Â÷·Î½á, ÃøÁ¤Ä¡¿¡ ´ëÇÑ º¸Á¤¿¡ ±Ù°ÅÇÑ ¾Ë°í¸®ÁòÀ» »ç¿ëÇÏ´Â ÀÏ¹Ý Ä¡·á°èȹ½Ã½ºÅÛ°ú ºñ½ÁÇÑ
¼öÁØÀ̶ó »ç·áµÈ´Ù. ÇöÀç·Î¼­´Â ÀüÀÚ¼±¿¡ ´ëÇÑ ¼±·®°è»êÀÌ ºÒ°¡´ÉÇϱ⠶§¹®¿¡ ¿ÏÀüÇÑ ÇüÅÂ
ÀÇ Ä¡·á°èȹ½Ã½ºÅÛÀÌ µÇ±â À§Çؼ­´Â ÇâÈÄ, ÀüÀÚ¼±¿¡ ´ëÇÑ °è»ê¸ðµâÀÇ °³¹ß°ú ±¤ÀÚ¼± ¼±·®°è
»ê ¶ÇÇÑ º¸´Ù Á¤¹ÐÇÑ ¼±·®°è»êÀÌ °¡´ÉÇÑ ÄÁ¹ú·ù¼Ç ¹æ¹ý°ú °°Àº 3Â÷¿ø ¼±·®°è»ê¸ðµâÀÇ °³¹ß
µµ ÇÊ¿äÇÏ´Ù. Plunc´Â »ó¾÷¿ë 3Â÷¿ø Ä¡·á°èȹ ½Ã½ºÅÛÀÇ »ç¿ëÀÌ Çö½ÇÀûÀ¸·Î ¾î·Á¿î ¿©°ÇÀÇ
º´¿ø¿¡¼­ 2Â÷¿ø Ä¡·á°èȹ½Ã½ºÅÛ°ú »óÈ£ º¸¿ÏÀûÀ¸·Î »ç¿ëÇÑ´Ù¸é 2Â÷¿ø Ä¡·á°èȹ½Ã½ºÅÛÀÌ °®
´Â ¸¹Àº Á¦¾àÀ» ±Øº¹ÇÒ ¼ö ÀÖÀ» °ÍÀ¸·Î »ç·áµÈ´Ù.

Purpose : The objective of this study is to introduce our installation of a
non-commercial 3D planning system, Plunc and confirm it's clinical applicability in
various treatment situations.
Materials and Methods : We obtained source codes of Plunc, offered by University of
North Carolina and installed them on a Pentium Pro 200MHz (128MB RAM, Millenium
VGA) with Linux operating system. To examine accuracy of dose distributions
calculated by Plunc, we input beam data of 6MV photon of our linear
accelerator(Siemens MXE 6740) including tissue-maximum ratio, scatter-maximum ratio,
attenuation coefficients and shapes of wedge filters. After then, we compared values of
dose distributions(Percent depth dose; PDD, dose profiles with and without wedge filters,
oblique incident beam, and dose distributions under air-gap) calculated by Plunc with
measured values.
Results : Plunc operated in almost real time except spending about 10 seconds in full
volume dose distribution and dose-volume histogram(DVH) on the PC described above
As compared with measurements for irradiations of 90-cm 553 and 10-cm depth
isocenter, the PBD curves calculated by Plunc did not exceed 1% of inaccuracies except
buildup region. For dose profiles with and without wedge filter, the calculated ones are
accurate within 2% except low-dose region outside irradiations where Plunc showed 5%
of dose reduction. For the oblique incident beam, it showed a goad agreement
except low dose region below 30 % of isocenter dose. In the case of dose distribution
under air-gap, there was 5% errors of the central-axis dose.
Conclusion : By comparing photon dose calculations using the Plunc with
measurements, we confirmed that Plunc showed acceptable accuracies about 2-5% in
typical treatment situations, which was comparable to commercial planning systems
using correction-based algorithms. Plunc does not have a function for electron beam
planning up to the present. However, it is possible to implement electron dose
calculation modules or more accurate photon dose calculation into the Plunc system.
Plunc is shows to be useful to clear many limitations of 2D planning systems in clinics
where a commercial 3D planning system is not available.

Å°¿öµå

3D planning system; CT simulation; Dose calculation algorithm;

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