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°£¾ÏȯÀÚ¿¡¼­ Electronic Portal Imaging Device(EPID)¸¦ ÀÌ¿ëÇÑ ÀÚ¼¼ ¿ÀÂ÷ ¹× Á¾¾ç À̵¿ °Å¸®ÀÇ °´°üÀû ÃøÁ¤ Measurements of Setup Error and Physiological Movement of Liver by Using Electronic Portal imaging Device in Patients with Hepatocellular Carcinoma

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±Ý±ââ/Ki Chung Keum ÀÌ»ó¿í/½ÅÇö¼ö/±è±Í¾ð/¼ºÁø½Ç/ÀÌâ°É/Ãß¼º½Ç/Àå¼¼°æ/¼­Ã¢¿Á/Sang Wook Lee/Hyun Soo Shin/Gwi Eon Kim/Jinsil Seong/Chang Geol Lee/Sung Sil Chu/Sei Kyung Chang/Chang Ok Suh

Abstract

¸ñÀû : °£¾ÏÀÇ 3Â÷¿ø ÀÔüÁ¶ÇüÄ¡·á°èȹ½Ã electronic portal imaging device (EPID)¸¦ ÀÌ¿ë
ÇÑ °ËÁõ¿µ»óÀ¸·Î °æ°è¿©À¯ °áÁ¤¿¡ ÇÊ¿äÇÑ °´°üÀû ±âÃÊÀڷḦ ¾òÀ¸¹Ç·Î½á ¹æ»ç¼±Ä¡·áÀÇ Á¤È®
¼ºÀ» ³ôÀÌ°í º» ±â±â¸¦ ÀÌ¿ëÇÏ¿© ¹æ»ç¼±Ä¡·áÀÇ Á¤µµ°ü¸® Ãø¸é¿¡¼­ÀÇ À¯¿ë¼ºÀ» ¾Ë¾Æº¸°íÀÚ
ÇÏ¿´´Ù.
´ë»ó ¹× ¹æ¹ý : 10¸íÀÇ °£¾Ï ȯÀÚ¿¡¼­ EPID¸¦ ÀÌ¿ëÇÏ¿© 1ȸ ¹æ»ç¼± Ä¡·á Áß ¾à 4-7ȸÀÇ
°ËÁõ¿µ»óÀ» ȹµæÇÏ¿´°í ÃÑ 10ȸ ºÐÇÒ Ä¡·á±â°£ µ¿¾È ¹Ýº¹ÇÏ¿© ½ÃÇàÇÏ¿´´Ù. ¹æ»ç¼±Ä¡·á ÀÚ¼¼
°íÁ¤½Ã ¹ß»ýÇÒ ¼ö ÀÖ´Â °¢ °³ÀÎÀÇ ÀÚ¼¼ ¿ÀÂ÷¸¦ ±¸ÇÏ¿© Ä¡·á°£ ¹ß»ýÇϴ ȯÀÚÀÇ À§Ä¡ À̵¿À»
ºÐ¼®ÇÏ¿´°í, È£ÈíÀ¸·Î ÀÎÇÑ °£ÀÇ »óÇÏ ¿òÁ÷ÀÓÀÇ Á¤µµ¸¦ ÃøÁ¤ÇÏ¿© °èȹ¿ëÇ¥ÀûüÀû(Planning
target Volume, PTV)ÀÇ °áÁ¤½Ã ÇÊ¿äÇÑ ÀûÁ¤ °æ°è¿©ºÎ¸¦ ±¸ÇÏ¿´´Ù.
°á°ú : °ËÁõ¿µ»ó ºÐ¼® °á°ú °£¾ÏÀÇ Ä¡·á½Ã ÀÚ¼¼À̵¿¿¡ ÀÇÇÑ ÀÚ¼¼ ¿ÀÂ÷´Â xÃàÀ¸·Î 3.0mm,
Ç¥ÁØÆíÂ÷´Â 1.70mm ¿´°í yÃàÀ¸·Î 3.7 mm, Ç¥ÁØÆíÂ÷ 1.88 mm ¿´´Ù. µû¶ó¼­ °¢ ÃàÀ» Áß½ÉÀ¸
·Î 5 mm À̳»¿´´Ù. ¶ÇÇÑ È£Èí¿¡ ÀÇÇÑ °£ÀÇ »óÇÏ ¿îµ¿ ¹üÀ§´Â Æò±Õ 8.63 mmÀ̾ú°í Ç¥ÁØÆí
Â÷´Â 1.48mm¿´´Ù. µû¶ó¼­ °èȹ¿ëÇ¥ÀûüÀû °áÁ¤½Ã Á¾¾ç¿¡ Àû¾îµµ 15 mmÀÇ °æ°è¿©À¯°¡ ´õ
ÇÊ¿äÇÏ´Ù.
°á·Ð : EPID´Â 3Â÷¿ø ÀÔüÁ¶ÇüÄ¡·á°èȹ½Ã Á¾¾çÀÇ °æ°è¿©À¯ °áÁ¤¿¡ ¸Å¿ì À¯¿ëÇÏ¸ç ³ª¾Æ°¡
¼­ ¹æ»ç¼± Ä¡·áÀÇ Á¤µµ°ü¸®¿¡µµ Å©°Ô ±â¿©ÇÒ °ÍÀÌ´Ù.

Purpose : The goal of this study was to improve th accuracy of three-dimensional
conformal radiotherapy (3-D CRT) by measuring the treatment setup error and
physiological movement of liver based on the analysis of images which were obtained
by electronic portal imaging device (EPID).
Materials and Methods : For 10 patients with hepatocellular carcinoma, 4-7 portal
images were obtained by using EPID during the radiotherapy from each patient daily.
We analyzed the setup error and physiological movement of liver based on the
verification data. We also determined the safely margin of the tumor in 3-D CRT
through the analysis of physiological movement.
Results : The setup errors were measured as 3 mm with standard deviation 1.70 mm
in x direction and 3.7 mm with standard deviation 1.88 mm in y direction respectively.
Hence, deviation were smaller than 5 mm from the center of each axis. The measured
range of liver movement due to the physiological motion was 8.63 mm on the average.
Considering the motion of liver and setup error, the safety margin of tumor was at least
15 mm.
Conclusion : EPID is a very useful device for the determination of the optimal margin
of the tumor, and thus enhance the accuracy and stability of the 3-D CRT in patients
with hepatocellular carcinoma.

Å°¿öµå

°£¾Ï; EPID; ¹æ»ç¼± Ä¡·á; Setup ¿ÀÂ÷; EPID; Hepatoma; Radiation treatment; Setup error;

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