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¼±Çü°¡¼Ó±â¸¦ ÀÌ¿ëÇÑ Á¤À§¹æ»ç¼± Ä¡·á ½Ã GafChromic FilmÀ» ÀÌ¿ëÇÑ ¼±·®ÃøÁ¤ GafChromic Film Dosimetry for Stereotactic Radiosurgery with a Linear Accelerator

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ÇѽÂÈñ/Seung Hee Han Á¶º´Ã¶/¹Ú¼®¿ø/¿ÀµµÈÆ/¹ÚÈñö/¹èÈƽÄ/Byung Chul Cho/Suk Won Park/Do Hoon Oh/Hee Chul Park/Hoon Sik Bae

Abstract

¸ñÀû: ¼±Çü°¡¼Ó±â¸¦ ÀÌ¿ëÇÑ Á¤À§¹æ»ç¼±Ä¡·á ½Ã GafChromic Çʸ§À» ÀÌ¿ëÇÏ¿© Á¶»çµÇ´Â ¼±·® ¹× ºÐÆ÷¸¦ ÃøÁ¤ÇÏ°í Ä¡·á °èȹ¿¡¼­ °è»êµÈ ¼±·®ºÐÆ÷¿ÍÀÇ ÀÏÄ¡ ¿©ºÎ¸¦ Æò°¡ÇÏ°íÀÚ ÇÏ¿´´Ù. ´ë»ó ¹× ¹æ¹ý: µÎºÎ ¸ðÇüÀÇ ¾ÆÅ©¸± ÆÒÅÒÀ» Á¦ÀÛÇÏ¿´´Âµ¥, ÆÒÅÒ Á߽ɰú ¶Ç ´Ù¸¥ µÎ
ÁöÁ¡¿¡¼­ Àü¸®ÇÔÀ» »ðÀÔÇϰųª, ÀÓÀÇ ´Ü¸é¿¡¼­ Çʸ§À» »ðÀÔÇÏ¿© Àý´ë¼±·® ¹× »ó´ë¼±·®ºÐÆ÷¸¦ ÃøÁ¤ÇÒ ¼ö ÀÖµµ·Ï ÇÏ¿´´Ù. GafChromic Çʸ§(MD-55-2, Nuclear Associate, USA)À» Æú¸®½ºÆ¼·» °íü ÆÒÅÒ ±íÀÌ 5 cm¿¡ »ðÀÔÇÏ¿© 6 MV ±¤ÀÚ¼±, 0~112 Gy ¼±·®À¸·Î Á¶»çÇÏ°í,
Digitizer¸¦ ÀÌ¿ëÇÏ¿© ÈæÈ­µµ(Optical density: OD)¸¦ ÃøÁ¤ÇÏ¿´´Ù. º»¿ø¿¡¼­ °³¹ßÇÑ Á¤À§¹æ»ç¼± Ä¡·á°èȹ½Ã½ºÅÛ 'Linapel'À» ÀÌ¿ëÇÏ¿© µÎºÎ ¸ðÇüÀÇ ¾ÆÅ©¸± ÆÒÅÒÀÇ Áß½ÉÁ¡(Isocenter of Target)À» ´ë»óÀ¸·Î, °¢°¢ÀÇ ºö¿¡ 300 cGy¼±·®ÀÌ Á¶»çµÇµµ·Ï 5 arc ºö Ä¡·á°èȹÀ»
½ÃÇàÇÏ¿´´Ù. Çʸ§¼±·®ÃøÁ¤½Ã½ºÅÛ(RIT113 ÇÁ·Î±×·¥)À» ÀÌ¿ëÇÏ¿© 5 arc ºö Àüü°¡ Á¶»çµÈ GafChromic Çʸ§ÀÇ »ó´ë¼±·®ºÐÆ÷¸¦ ÃøÁ¤ÇÏ°í Ä¡·á°èȹ¿¡¼­ °è»êµÈ ¼±·®ºÐÆ÷¿Í ºñ±³ÇÏ¿´´Ù. °á°ú: MD-55-2 GafChromicÇʸ§¿¡ ´ëÇÑ ÈæÈ­µµ´Â Á¶»çµÈ ¼±·®¿¡ ´ëÇÏ¿© ¼±Çü¼ºÀ» °¡Áö°í
ÀÖÀ½À» È®ÀÎÇÏ¿´´Ù. ±íÀÌ º¯È­¿¡ ´ëÇÑ ¼±·® °ªÀÇ º¯È­¿Í ºöÀÇ È¾Ãà¿¡ ´ëÇÑ ºö Ãø¸é»ó(profile)µµ GafChromic Çʸ§À» ÀÌ¿ëÇÏ¿© ÃøÁ¤ÇÒ ¼ö ÀÖ¾ú´Ù. Ä¡·á°èȹ½Ã½ºÅÛ 'Linapel'À» ÀÌ¿ëÇÑ Ä¡·á°èȹÀÇ ¼±·® °è»ê °ª°ú ÃøÁ¤¿¡¼­ ¾òÀº Àý´ë¼±·® °ªÀ» ºñ±³ÇÏ¸é ¿ÀÂ÷¹üÀ§°¡ +/-3%
À̳»¿¡ ÀÖÀ½À» È®ÀÎÇÏ¿´´Ù. GafChromic Çʸ§ÀÇ ½ÇÁ¦ Á¶»çµÈ »ó´ë¼±·®ºÐÆ÷µµ¸¦ Ä¡·á °èȹ¿¡¼­ °áÁ¤µÈ ¼±·®ºÐÆ÷µµ¿Í ºñ±³Çϸé 50~90%¿¡ ´ëÇÏ¿© +/-1 mmÀÇ Â÷À̸¦ °¡Áö°í ÀÖÀ½À» È®ÀÎÇÒ ¼ö ÀÖ¾ú´Ù. °á·Ð: º» ¿¬±¸¸¦ ÅëÇÏ¿© GafChromic Çʸ§Àº Àý´ë¼±·®°ú »ó´ë¼±·®ºÐÆ÷¸¦
ÃøÁ¤ÇÒ ¼ö ÀÖ´Ù´Â °ÍÀ» È®ÀνÃÄÑ ÁÜÀ¸·Î½á, ¼±Çü°¡¼Ó±â¸¦ ÀÌ¿ëÇÏ´Â Á¤À§¹æ»ç¼±Ä¡·á¿¡¼­ Ä¡·á Àü¿¡ ¼±·®ÃøÁ¤À» À§ÇÑ ¹æ¹ýÀ¸·Î ¹ÏÀ» ¸¸ÇÑ Á¤º¸¸¦ Á¦°øÇÒ ¼ö ÀÖ´Â ¹æ¹ýÀ¸·Î »ý°¢µÈ´Ù.

PURPOSE: The purpose of this study was to evaluate whether a GafChromic film applied to stereotactic radiosurgery with a linear accelerator could provide information on the value for acceptance testing and quality control on the absolute dose and
relative dose measurements and/or calculation of treatment planning system. MATERIALS AND METHODS: A spherical acrylic phantom, simulating a patient's head, was constructed from three points. The absolute and relative dose distributions could be
measured by inserting a GafChromic film into the phantom. We tested the use of a calibrated GafChromic film (MD-55-2, Nuclear Associate, USA) for measuring the optical density. These measurements were achieved by irradiating the films with a dose of
0-112 Gy employing 6 MV photon. To verify the accuracy of the prescribed dose delivery to a target isocenter using a five arc beams (irradiated in 3 Gy per one beam) setup, calculated by the Linapel planning system the absolute dose and relative dose
distribution using a GafChromic film were measured. All the irradiated films were digitized with a Lumiscan 75 laser digitizer and processed with the RIT113 film dosimetry system. RESULTS: We verified the linearity of the Optical Density of a MD-55-2
GafChromic film, and measured the depth dose profile of the beam. The absolute dose delivered to the target was close to the prescribed dose of Linapel within an accuracy for the GafChromic film dosimetry (of +/-3%), with a measurement uncertainty of
+/-1 mm for the 50~90% isodose lines. CONCLUSION: Our results have shown that the absolute dose and relative dose distribution curves obtained from a GafChromic film can provide information on the value for acceptance. To conclude the GafChromic film is
a convenient and useful dosimetry tool for linac based radiosurgery.

Å°¿öµå

Á¤À§¹æ»ç¼±Ä¡·á; GafChromic Çʸ§; Àý´ë¼±·®; »ó´ë¼±·®; ÈæÈ­µµ; Stereotactic radiosurgery; GafChromic film; Absolute dose; Relative dose; Optical density;

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