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Á¶±â À¯¹æ¾Ï¿¡¼­ À¯¹æº¸Á¸Ä¡·á¿Í À¯¹æÀýÁ¦¼ú Ä¡·á¼ºÀû ºñ±³ A Comparison of Clinical Outcomes for Breast-conserving Treatment and Mastectomy for Early Breast Cancer

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¾çÁ¤Çö ( Yang Jung-Hyun ) 
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ÀÓ¿µÇõ ( Im Young-Hyuck ) 
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Abstract

¸ñÀû: Á¶±â À¯¹æ¾Ï¿¡¼­ À¯¹æº¸Á¸Ä¡·á¿Í À¯¹æÀýÁ¦¼úÀÇ Ä¡·á ¼ºÀûÀ» ºñ±³ÇÏ°í, ¿¹ÈÄ ÀÎÀÚ¸¦ ¾Ë¾Æº¸°íÀÚ ÇÏ¿´´Ù.

´ë»ó ¹× ¹æ¹ý: 1994³â 9¿ùºÎÅÍ 2002³â 12¿ù±îÁö º»¿ø¿¡¼­ ±ÙÄ¡Àû ¼ö¼úÀ» ¹ÞÀº º´¸®ÇÐÀû º´±â T1~2N0 À¯¹æ¾Ï ȯÀÚ 1,200¸íÀ» ÈÄÇâÀûÀ¸·Î ºÐ¼®ÇÏ¿© À¯¹æº¸Á¸Ä¡·á¿Í À¯¹æÀýÁ¦¼úÀ» »çÀÌÀÇ Â÷À̸¦ ºñ±³ÇØ º¸¾Ò´Ù.

°á°ú: ºÐ¼®¿¡ Æ÷ÇÔµÈ 1,174¸íÀÇ È¯ÀÚ Áß 601¸íÀÌ(51.2%) À¯¹æº¸Á¸Ä¡·á¸¦ ¹Þ¾Ò°í 573¸íÀÌ(48.8%) À¯¹æÀýÁ¦¼úÀ» ¹Þ¾Ò´Ù. À¯¹æÀýÁ¦¼úÀ» ¹ÞÀº ±º¿¡¼­ À¯ÀÇÇÏ°Ô Á¾¾çÀÇ Å©±â°¡ ÄÇ°í, ´Ù¹ß¼º(multicentricity), ¿¡½ºÆ®·Î°Õ ¹× ÇÁ·Î°Ô½ºÅ×·Ð ¼ö¿ëü À½¼º µîÀÇ ÀÎÀÚ°¡ ´õ ¸¹Àº °æÇâÀ» º¸¿´´Ù. À¯¹æº¸Á¸Ä¡·á ¹× À¯¹æÀýÁ¦¼úÀ» ¹ÞÀº ȯÀÚÀÇ 10³â »ýÁ¸À²Àº °¢°¢ 91.96%¿Í 91.01%¿´°í(p=0.1274), 10³â ¹«º´»ýÁ¸À²Àº °¢°¢ 80.48%¿Í 84.95% (p=0.8795)·Î À¯ÀÇÇÑ Â÷À̸¦ º¸ÀÌÁö ¾Ê¾Ò´Ù

°á·Ð: Á¶±â À¯¹æ¾Ï¿¡¼­ À¯¹æº¸Á¸Ä¡·á ³»Áö´Â À¯¹æÀýÁ¦¼úÀ» ¹ÞÀº ±º »çÀÌ¿¡ ȯÀÚ Æ¯¼ºÀÇ Â÷ÀÌ´Â ÀϺΠÀÖ¾úÀ¸³ª »ýÁ¸À²
¿¡¼­ À¯ÀÇÇÑ Â÷À̸¦ º¸ÀÌÁö ¾Ê¾Ò´Ù.

Purpose: To compare the treatment outcomes and to analyze prognostic factors between the use of a breast-conserving treatment (BCT) and a mastectomy for early stage breast cancer.

Materials and Methods: We retrospectively reviewed 1,200 patients with pathological stage T1-2N0 breast cancer who received surgery between September 1994 and December 2002 at Samsung Medical Center. We compared the patient characteristics and treatment outcomes between the two treatment groups.

Results: Among the 1,174 eligible patients, 601 (51.2%) patients received a BCT and the remaining 573 (48.8%) patients received a mastectomy. The mastectomy group of patients had significantly more cases with a larger tumor size, multicentricity, extensive intraductal component, and estrogen- and progesterone- receptor negativity. The ten-year overall survival rates (OS) of the BCT and mastectomy groups were 91.96% and 91.01%, respectively (p=0.1274). The ten-year disease-free survival rates (DFS) were 80.48% for the BCT group of patients and 84.95% for the mastectomy group of patients, respectively (p=0.8795).

Conclusion: Our study shows some differences in patient characteristics between the two treatment groups.
However, these differences did not result in significant survival differences.

Å°¿öµå

À¯¹æ¾Ï;À¯¹æº¸Á¸Ä¡·á;À¯¹æÀýÁ¦¼ú
Breastcancer;Breast-conservingsurgery;Mastectomy

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KoreaMed
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