만성 염증성 탈수초성 신경병증: 당뇨병 유무에 따른 임상적, 전기생리학적 소견의 비교
Chronic Inflammatory Demyelinating Poly neuropathy: Comparison of Clinical and Electrophsiological Features in Patients with and without Diabetes
권석범, 권기한, 정산, 조수진, 민양기, 최휘철, 황성희,
소속 상세정보
권석범 ( Kwon Seok-Beom )
한림대학교 의과대학 신경과학교실
권기한 ( Kwon Ki-Han )
한림대학교 의과대학 신경과학교실
정산 ( Jung San )
한림대학교 의과대학 신경과학교실
조수진 ( Cho Soo-Jin )
한림대학교 의과대학 신경과학교실
민양기 ( Minn Yang-Ki )
한림대학교 의과대학 신경과학교실
최휘철 ( Choi Hui-Chul )
한림대학교 의과대학 신경과학교실
황성희 ( Hwang Sung-Hee )
한림대학교 의과대학 신경과학교실
KMID : 0860920040060010016
Abstract
Objectives: There is growing evidence that idiopathic chronic inflammatory demyelinating polyneuropathy
(I-CIDP) and polyneuropathy in patients with diabetes mellitus (DM) that meets the clinical and
electrophysiological criteria for CIDP (DM-CIDP) have many similarities. We performed this study to
determine whether a subset of DM-CIDP are similar to I-CIDP employing proposed clinical and electrophysiologic
criteria for CIDP.
Methods: We compared the clinical (age, sex, symptom duration, pattern, course, motor scale, sensory
scale, total clinical scale, and M-Rankin score, etc.) and electrodiagnostic (routine nerve conduction studies
including median, ulnar, peroneal, and posterior tibial nerves) features of 9 patients (M=5, F=4) with
DM-CIDP to those of 11 patients (M=4, F=7) with I-CIDP.
Results: The patients with DM-CIDP displayed clinical, electrophysiologic features that were similar to
those in patients with I-CIDP.
Conclusion: Our study showed the influences of diabetes in patients with CIDP are insignificant and
DM-CIDP is electrophysiologically indistinguishable from idiopathic CIDP. It is important to separate
immune-mediated, demyelinating polyneuropathy in diabetic patients (DM-CIDP) from axonal polyneuropathy
because the former responds to immunomodulatory treatment.
키워드
Short segment nerve conduction study;sensitivity
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