척수손상 환자의 난치성 경직에서 척수강 내 바클로펜 투여 후 시간에 따른 변화 양상
Swrial Changes After the Trial Use of Bolus Intrathrcal Baclofen for Intractable Spasticity of Spinal Cord Injury Patients
고현윤, 박재흥, 양진환,
소속 상세정보
고현윤 ( Ko Hyun-Yoon )
부산대학교 의과대학 재활의학교실
박재흥 ( Park Jae-Heung )
부산대학교 의과대학 재활의학교실
양진환 ( Yang Jin-Hwan )
부산대학교 의과대학 재활의학교실
KMID : 0860920040060010052
Abstract
Objective: This study was conducted to add to the information for preselexrion of intrathecal baclofen (ITB) pump and to evaluate serial changes after the trial use of bolus ITB for intractable spasticity of spinal cord injury (SCI) patients.
Method: Ten SCI patients with severe intractable spasticity who had failed oral antispastic were measured using H/M ratio, Ashworth Scale, Spasm scale and Reflex scale.
Results: There was a significant decrease in spasticity in all patients. After injection of ITB, decreased amount of spasticity for 1 hour was as follows: H/M ratio, 50.34±7.35%; Ashworth Scale, 9.85±5.33%; Spasm scale 34.92±5.86%; Reflex sxale 14.26±4.46%. minimal hours for maximal effect of recovery of spasticity were the next: H/M ratio, 6.0±0.0; Ashworth Scale, 7.9±0.6; Spam scale 9.6±0.7; Reflex scale 8.4±1.1. H/M ratio had a meaningful changes after th trial use of bolus ITB for 1 hour and in minimal hours for maximal effect of spasticity.
Conclusion:Ten SCI patients responded with a reduction in H/M ratio, Ashworth Scale, spasm scale and Reflex scale scores more than two points in ITB bolus trial. H/M ratio are the most sensitive indicator of serial changes after the trial use of bolus ITB for intractable spasticity of SCI patients.
키워드
Intrathecal baclofen (ITB);Spasticity;Spinal cord injury (SCI)
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