만성알코올중독 환자에서 시행한 체성감각유발전위와 신경전도검사
Somatosensory Evokde Potentials and Nerve Conduction Studies in Patients with Chronic Alcoholism
김우경, 최영철, 채경민, 박현정, 최희찬, 이주헌, 송홍기,
소속 상세정보
김우경 ( Kim Woo-Kyung )
한림대학교 의과대학 신경과학교실
최영철 ( Choi Young-Chul )
연세대학교 의과대학 신경과학교실
채경민 ( Chae Kyoung-Min )
연세대학교 의과대학 신경과학교실
박현정 ( Park Hyun-Jung )
한림대학교 의과대학 신경과학교실
최희찬 ( Choi Hee-Chan )
한림대학교 의과대학 신경과학교실
이주헌 ( Lee Ju-Hun )
한림대학교 의과대학 신경과학교실
송홍기 ( Song Hong-Ki )
한림대학교 의과대학 재활의학교실
KMID : 0860920040060020177
Abstract
Objectives: Alcohol is one of the main causes for polyneuropathy and only total abstinence from alcohol
can give a chance of regeneration or halt of the disease. Therefore, early diagnosis and treatment are
essential for public health problem. Nerve conduction studies are commonly used to evaluate the function
of large myelinated fibers, and are often found to be within normal limits in an early state of polyneuropathy.
We assessed somatosensory evoked potentials to determine usefulness in detecting electrophysiologic
abnormalities in the early state of polyneuropathy in alcoholics.
Methods: We performed nerve conduction studies and somatosensory evoked potentials from posterior
tibial nerve stimulation in alcoholic patients having clinical symptoms or signs of polyneuropathy.
Among them, we recruited 15 alcoholics who had normal values of nerve conduction studies. Control
subjects were age and height matched 18 healthy volunteers.
Results: The mean latency of spinal evoked potentials was 22.4 msec for the control subjects and 21.5
msec in for the alcoholics. The mean latency of cortical evoked potentials was 39.3 msec and 41.3 msec
respectively. The cortical evoked potentials were significantly prolonged in alcoholics compared to control
subjects. The mean central conduction time was not different between groups.
Conclusions: This study demonstrate that the latency of cortical evoked potentials is prolonged in the
alcoholics with clinically suspected polyneuropathy and the somatosensory evoked potentials can be a
useful diagnostic test for early detection of alcoholic polyneuropathy.
키워드
Alcoholism;somatosensory evokde potentials(SEP);Nerve conduction study
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