보툴리눔 톡신 A(디스포트 ) 주사로 호전된 원발성 구개근 경련
Essential Palatal Myoclonus treated with Botulinum Toxin A (Dysport )
고영진, 이종인, 김종현, 임지은, 홍현택, 박시내, 최항준,
소속 상세정보
고영진 ( Ko Young-Jin )
가톨릭대학교 의과대학 재활의학교실
이종인 ( Lee Jong-In )
가톨릭대학교 의과대학 재활의학교실
김종현 ( Kim Jong-Hyun )
가톨릭대학교 의과대학 재활의학교실
임지은 ( Lim Ji-Eun )
가톨릭대학교 의과대학 재활의학교실
홍현택 ( Hong Hyeon-Taek )
가톨릭대학교 의과대학 재활의학교실
박시내 ( Park Shi-Nae )
가톨릭대학교 의과대학 이비인후과학교실
최항준 ( Choi Hang-Joon )
가톨릭대학교 의과대학 재활의학교실
KMID : 0860920050070010050
Abstract
Palatal myoclonus is an uncommon movement disorder involving soft palate or oropharyngeal muscles innervated by cerebral or spinal nerves. A variety of different etiologies of palatal myoclonus have been described, including cerebrovacular disease, multiple sclerosis, meningoencephalitis, infectious disease, head trauma, neoplasm, Alexander syndrome or other congenital malformation of the brain. It can be idiopathic, but it is extremely rare. Rhythmical and involuntary contractions of soft palate make tinnitus and otalgia, and it can be heard by observer. Pharmacotheraphy for palatal myoclonus include carbamazepine, tryptophan, lamotrigine, but none of these treatments has been consistently effective. We present here a case of essential palatal myoclonus treated with Clostridium botulinum toxin A (Dysport?)
injection into bilateral tensor veli palatini muscles guided by electromyography and endoscopy. Tinnitus and otalgia were vanished 2 days after injection. Needle electromyography showed decreased MUAPs (motor unit action potentials) as time goes by.
키워드
Palatal myoclonus;Botulinum toxin;Tinnitus;Otalgia
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