울릉미역취 에탄올추출물의 항산화 활성
Antioxidant Activities of Ethanol Extracts from Solidago virga-aurea var. gigantea
지윤선, 이남선, 길기정, 유지현,
소속 상세정보
지윤선 ( Ji Yoon-Sun )
중부대학교 한방보건제약학전공
이남선 ( Lee Nam-Sun )
중부대학교 한방보건제약학전공
길기정 ( Kil Ki-Jung )
중부대학교 한방보건제약학전공
유지현 ( Yoo Ji-Hyun )
중부대학교 한방보건제약학전공
Abstract
Objectives : This study aimed to analyze contents of chlorogenic acid among major ingredients and determine the optimal solvent for the antioxidant activity from Solidago virga-aurea var. gigantea(SV) aerial part.
Methods : Mature aerial part of extracted SV at the first crop on June 2018 was used. SV was mixed with each at the ethanol concentrate rates of water, 10, 30, 50, 70, and 100% and extracted them for three times for eight hours at 70℃. The contents of chlorogenic acid and seven kinds of antioxidant activities were measured in SV extracts.
Results : The highest the contents of chlorogenic acid was from 10% ethanol extracts showed. Total polyphenol and flavonoids of SV extracts were 126.16 mg/g and 105.84 mg/g, respectively. Scavenging activities of DPPH, ABTS, and hydroxyl radical significantly increased in a dose-dependent in SV extracts, while it was almost similar with control at the concentration of 500 g/mL. Fe2+ chelating activity significantly increase in a dose-dependent in SV extract, it was lower than control.
Nitrite scavenging activity increased, dose-dependent in the sequence of pH 1.2> pH 3.0 > pH 6.0 in SV extracts, while it was almost similar with control at the concentration of 500 g/mL, pH 1.2, and pH 3.0.
Conclusions : Thus, this study found that higher contents of chlorogenic acid and excellent antioxidant activity were contained in 10% ethanol extracts in mature aerial part of SV. It is expected to be used as basic data as natural antioxidant materials.
키워드
Solidago virgaurea; Antioxidant; Ethanol Extracts; Chlorogenic acid; Aerial part
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