Ketamine으로 치료한 난치성 간질 중첩 환자 2예
Two Cases of Refractory Status Epilepticus Treated with Ketamine
이지연, 박성민, 김영인,
소속 상세정보
이지연 ( Lee Ji-Youn )
가톨릭대학교 의과대학 신경과학교실
박성민 ( Park Seong-Min )
가톨릭대학교 의과대학 신경과학교실
김영인 ( Kim Yeong-In )
가톨릭대학교 의과대학 신경과학교실
KMID : 0877220010050010082
Abstract
Clinical observations and recent experimental studies have suggested that the longer status epilepticus (SE) persists, the more difficult it is to control SE pharmacologically. These findings imply that there are fundamental pathophysiologic processes, which make more resistant to intervene in the refractory SE. Recently, it has been recognized that ketamine, N-methyl-D-aspartate receptor antagonists, are effective agents in the treatment of the late stages of SE in the animal model. However, only one clinical experience has been reported. Here, we report two cases with refractory SE, responsive to ketamine.
키워드
난치성 간질 중첩증; NMDA 수용체 길항제(Ketamine)
Refractory status epilepticus; N-methyl-D-aspartate receptor antagonist; Ketamine
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